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For many, the onset of colder weather is a reminder to slow down, take stock, and appreciate the simple pleasures in life. It is a time to gather with loved ones around a crackling fire, to savor hearty meals that warm the soul, and to reflect on the passing of time as another year draws to a close. The chill in the air serves as a gentle nudge to embrace the changing seasons and to find joy in the small moments of everyday life.

As the photos and videos of Xiaohua's impeccable work continued to circulate online, fans and followers expressed their admiration for the hairstylist's talent and professionalism. Many praised Xiang Zuo for trusting Xiaohua with his hair and allowing him to showcase his skills. The incident not only drew attention to Xiaohua and Xiang Zuo but also highlighted the importance of a good hairstylist in the world of celebrities.

In a move that has sent shockwaves through the tech industry, reports have emerged that Intel is considering appointing Apple's chip expert Johny Srouji as the company's new CEO. This bold decision by Intel reflects the shifting landscape of the semiconductor market, as the company aims to revitalize its position and drive innovation in the face of fierce competition.Report Napoli want Juventus veteran Danilo in January

(BPT) - This article was sponsored and developed by Neurocrine Biosciences, Inc. Cerebral palsy (CP) is a neurodevelopmental disorder affecting movement and posture that begins in early childhood development. It is the most common cause of motor disability in children, affecting about one in 345 children in the United States. 1-2 It may happen as a result of lack of oxygen during or around birth, stroke, infection, a problem with metabolism or other problems that cause injury or affect the development of parts of the brain involved in movement control in the first few years of life. 3 CP is a permanent condition, affecting a person for their entire life. People living with CP typically have motor problems, which may include spasticity (abnormal muscle tightness), dyskinesia (uncontrolled movements) or ataxia (poor muscle control), and many people have a mix of these motor disorders. 4 Dyskinesia due to CP (DCP) is one of the most disabling forms of CP and impacts approximately 10% to 20% of people living with CP. 5-6 According to the Cerebral Palsy Foundation (CPF), the combination of irregular and unpredictable movements (chorea) and twisting and repeating movements (dystonia) often disrupt activities and cause significant functional impairment, including the ability to maintain balance, walk or fine motor control. 7 Heather Riordan, M.D., Neurologist and Movement Disorders Specialist, Director of the Phelps Center for Cerebral Palsy at the Kennedy Krieger Institute, discusses the symptoms of chorea and impact on patients in a video shared on the CPF website here . About 30% of people with DCP are affected mostly by these involuntary and irregular movements (chorea), while dystonia is the predominant motor finding in the remaining 70%. 8 However, it is common for both chorea and dystonia movements to be present together. 6 For people living with DCP, these movements can occur in any region of the body, including the arms and legs, torso and face and may vary in severity. They are often triggered or made worse by stimulation or stress. Because dyskinesia can occur at rest and/or when actively using the body, the problems with movement are very burdensome in day-to-day living, with discomfort and pain affecting the quality of life for people and their caregivers. 9 Jen Lyman, mom to a son with DCP, highlights how dyskinesia makes communicating more difficult. "The most difficult thing about dyskinesia is watching my son struggle to do things that he wants to do, but the extra movements get in the way...special things, such as using a touch screen to video chat with his grandmother, are nearly impossible despite his best efforts to use his hands and fingers. Something so simple, yet so special for him should be effortless." DCP has a wide-ranging impact on the individual, including lifelong challenges with movement, a higher risk of other medical issues, a higher rate of mental health challenges and difficulties with communication. 10-12 "Those of us who have the privilege to serve patients with dyskinetic, hyperkinetic or mixed cerebral palsy see the functional impact of this very challenging type of tone every day," said Susan Biffl, M.D., Rehabilitation Medicine Specialist at Rady Children's Hospital-San Diego and Assistant Professor at UC San Diego School of Medicine. "Patients face challenges with self-care, independence, mobility, communication, fine motor skills that affect occupational and recreational activities, swallowing, social interactions and even sleep. As this tone is variable, it is much more challenging to treat than more consistent tone issues, such as spasticity." Treatment Options There are currently no Food and Drug Administration-approved treatments for DCP. Dystonia and chorea are often managed separately as they respond differently to various treatments, which can make treatment challenging. 3 Most drugs being investigated for DCP have focused on dystonia, and more research is needed to determine potential treatments for chorea. New treatment options are needed to help manage these movement disorders and improve daily function and quality of life for those affected. "After 20 years of caring for individuals with cerebral palsy, I continue to find those with dyskinetic cerebral palsy among the most challenging to treat, largely due to the limited effectiveness of available pharmacologic options," said Joyce Oleszek, M.D., Professor, Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine. "There is an urgent need for more robust evidence to support pharmacologic treatments for this condition, given its profound impact on function, comfort and quality of life." Ongoing Research Clinical studies are important in the development of treatment options, allowing researchers to evaluate the safety and effectiveness of new medicines. The data from clinical studies are used to determine if an investigational treatment can be approved for use to treat certain disorders. There are ongoing clinical studies evaluating potential treatments for DCP, including one for chorea. Neurocrine Biosciences is conducting the KINECT ® -DCP clinical study, a Phase 3, randomized, double-blind placebo-controlled study investigating the study drug, valbenazine, for the treatment of DCP. The clinical study is currently enrolling children, adolescents and adults six to 70 years of age who have been diagnosed with DCP. "The Cerebral Palsy Foundation is excited to partner with Neurocrine Biosciences on this study," said Rachel Byrne, Executive Director of the Cerebral Palsy Foundation. "We are proud to support strong research that can potentially bring meaningful change to the lives of those living with cerebral palsy." If you or someone you know may be eligible for this research study, please visit the study website for additional information here: FindADCPStudy.com . REFERENCES © 2024 Neurocrine Biosciences, Inc. All Rights Reserved. CAP-NBI-US-0115 12/2024 NBI-98854-DCP3018_11DecMatRelease_v1.0_25November2024None

Karine Jean-Pierre claims ‘war politics’ is the reason for Hunter Biden pardon | Reporter ReplayIn a shocking and devastating turn of events, a man's 20-year addiction to betel nut chewing has resulted in him becoming a victim of self-inflicted facial disfigurement. This tragic incident serves as a stark reminder of the dangers of long-term harmful habits and the destructive consequences they can have on one's health and well-being.

In addition to accountability, Ferdinand also stresses the importance of clear communication and transparency in dealing with underperforming players. Rather than avoiding difficult conversations or hesitating to make tough decisions, Ferdinand believes that the club's management should be straightforward and honest in their assessments of players' performances. By setting clear expectations and providing constructive feedback, Manchester United can help underperforming players improve or make necessary changes to the squad to maintain competitiveness.

Bowls miss out in 4 CFP teams in latest postseason twistThese recent developments underscore the dynamic nature of the technology landscape and the continuous evolution of industry trends. From regulatory scrutiny shaping market dynamics to innovative product launches redefining consumer experiences, the intersection of technology and innovation remains a fascinating terrain to explore. As we navigate through the ever-changing tech ecosystem, it is essential to stay informed, vigilant, and open to the possibilities that await in the realm of science, technology, and creativity.Politics live chat: the Star's Ottawa reporters take your questions on the year in politics

Dyskinetic Cerebral Palsy: A Closer Look at Symptoms, Diagnosis and Clinical Research UnderwayJACKSONVILLE, Fla. — Greg McGarity had reason to be concerned. The Gator Bowl president kept a watchful eye on College Football Playoff scenarios all season and understood the fallout might affect his postseason matchup in Jacksonville. What if the Southeastern Conference got five teams into the expanded CFP? What if the Atlantic Coast Conference landed three spots? It was a math problem that was impossible to truly answer, even into late November. Four first-round playoff games, which will end with four good teams going home without a bowl game, had the potential to shake up the system. The good news for McGarity and other bowl organizers: Adding quality teams to power leagues — Oregon to the Big Ten, Texas to the SEC and SMU to the ACC — managed to ease much of the handwringing. McGarity and the Gator Bowl ended up with their highest-ranked team, No. 16 Ole Miss, in nearly two decades. "It really didn't lessen our pool much at all," McGarity said. "The SEC bowl pool strengthened with the addition of Texas and Oklahoma. You knew they were going to push traditional SEC teams up or down. Texas ended up pushing just about everyone down." The long waiting game was the latest twist for non-CFP bowls that have become adept at dealing with change. Efforts to match the top teams came and went in the 1990s and first decade of this century before the CFP became the first actual tournament in major college football. It was a four-team invitational — until this year, when the 12-team expanded format meant that four quality teams would not be in the mix for bowl games after they lose next week in the first round. "There's been a lot of things that we've kind of had to roll with," said Scott Ramsey, president of the Music City Bowl in Nashville, Tennessee. "I don't think the extra games changed our selection model to much degree. We used to look at the New York's Six before this, and that was 12 teams out of the bowl mix. The 12-team playoff is pretty much the same." Ramsey ended up with No. 23 Missouri against Iowa in his Dec. 30 bowl. A lot of so-called lesser bowl games do have high-profile teams — the ReliaQuest Bowl has No. 11 Alabama vs. Michigan (a rematch of last year's CFP semifinal), Texas A&M and USC will play in the Las Vegas Bowl while No. 14 South Carolina and No. 15 Miami, two CFP bubble teams, ended up in separate bowls in Orlando. "The stress of it is just the fact that the CFP takes that opening weekend," Las Vegas Bowl executive director John Saccenti said. "It kind of condenses the calendar a little bit." Bowl season opens Saturday with the Cricket Celebration Bowl. The first round of the CFP runs Dec. 20-21. It remains to be seen whether non-CFP bowls will see an impact from the new dynamic. They will know more by 2026, with a planned bowl reset looming. It could include CFP expansion from 12 to 14 teams and significant tweaks to the bowl system. More on-campus matchups? More diversity among cities selected to host semifinal and championship games? And would there be a trickle-down effect for everyone else? Demand for non-playoff bowls remains high, according to ESPN, despite increased focus on the expanded CFP and more players choosing to skip season finales to either enter the NCAA transfer portal or begin preparations for the NFL draft. "There's a natural appetite around the holidays for football and bowl games," Kurt Dargis, ESPN's senior director of programming and acquisitions, said at Sports Business Journal's Intercollegiate Athletics Forum last week in Las Vegas. "People still want to watch bowl games, regardless of what's going on with the playoff. ... It's obviously an unknown now with the expanded playoff, but we really feel like it's going to continue." The current bowl format runs through 2025. What lies ahead is anyone's guess. Could sponsors start paying athletes to play in bowl games? Could schools include hefty name, image and likeness incentives for players participating in bowls? Would conferences be willing to dump bowl tie-ins to provide a wider range of potential matchups? Are bowls ready to lean into more edginess like Pop-Tarts has done with its edible mascot? The path forward will be determined primarily by revenue, title sponsors, TV demand and ticket sales. "The one thing I have learned is we're going to serve our partners," Saccenti said. "We're going to be a part of the system that's there, and we're going to try to remain flexible and make sure that we're adjusting to what's going on in the world of postseason college football." Get local news delivered to your inbox!The positive trends in various sectors of the economy can be attributed to the effective deployment of a "combination punch" of policy measures by the government. Fiscal stimulus, monetary easing, targeted support for small and medium-sized enterprises, and infrastructure investments have all played a crucial role in stabilizing the economy and boosting confidence among businesses and consumers.Trump aims to appoint son-in-law’s father as US ambassador to France

Title: Major 5.7 Magnitude Earthquake Strikes Nevada, USA with Epicenter 10 Kilometers Deep AP Sports SummaryBrief at 5:33 p.m. EST

The home of the Sounders may now officially become the home for a country during the 2026 FIFA Men’s World Cup. FIFA announced an updated list of potential base camps for countries participating in the World Cup on Thursday that included the Sounders new training center at the former Longacres site in Renton. Adding the Sounders training center is an announcement that’s long been expected and was probably amplified by the visit last month from FIFA President Gianni Infantino to the area that also included a reception and tour of the facility. Seattle is set to host six matches during the tournament beginning in June 2026 – four in the group stage, one in the round of 32 and one in the round of 16. But cities can often serve as both host venues and base camps for various countries. For example, during the 2018 World Cup in Russia, the city of Sochi hosted matches while also being the base camp for Brazil and Poland at a couple of venues around the area. The Sounders facility was one of 26 new options added by FIFA that also included a couple of other potential sites in the Pacific Northwest. Across the state, Gonzaga University in Spokane is listed as a possible base camp. The Bulldogs’ Luger Field is a grass soccer stadium on the bank of the Spokane River. Another site in the region listed was Boise State University where the Broncos play at the Boas Soccer Complex. Any of the three Pacific Northwest locations would seem likely options for a country that ends up with the majority of its group stage games on the West Coast. Other cities are expected to be added as potential base camps for the 48 participating countries throughout 2025. Portland is not currently listed as a possible base camp but would seem a likely candidate with a few options in the area. The final decisions on what cities each country will call home for the tournament are expected a little over a year from now, shortly after the draw. The draw to set the groups and schedule for the tournament is expected to take place in December 2025.

NoneThe story of Lin Jing'en's fall from grace and her subsequent transformation into a homeless wanderer served as a cautionary tale for those who sought fame and fortune at any cost. It was a stark reminder that the trappings of celebrity could easily crumble, leaving behind only the fragile remnants of a once glittering life.The significance of TSMC's victory in this critical battle cannot be overstated. The 3nm process represents the pinnacle of semiconductor technology, offering unparalleled performance, power efficiency, and scalability. By successfully securing orders from key clients for the 3nm process, TSMC has reinforced its position as a global leader in advanced semiconductor manufacturing.