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Avior Wealth Management LLC reduced its position in Repligen Co. ( NASDAQ:RGEN – Free Report ) by 68.7% in the 3rd quarter, according to its most recent filing with the SEC. The firm owned 826 shares of the biotechnology company’s stock after selling 1,812 shares during the period. Avior Wealth Management LLC’s holdings in Repligen were worth $123,000 at the end of the most recent reporting period. Several other hedge funds and other institutional investors also recently made changes to their positions in RGEN. Andra AP fonden acquired a new stake in shares of Repligen during the second quarter worth $25,000. International Assets Investment Management LLC acquired a new stake in shares of Repligen during the second quarter worth $33,000. UMB Bank n.a. grew its stake in shares of Repligen by 138.3% during the third quarter. UMB Bank n.a. now owns 224 shares of the biotechnology company’s stock worth $33,000 after purchasing an additional 130 shares during the period. Lazard Asset Management LLC grew its stake in shares of Repligen by 206.1% during the first quarter. Lazard Asset Management LLC now owns 202 shares of the biotechnology company’s stock worth $36,000 after purchasing an additional 136 shares during the period. Finally, Blue Trust Inc. grew its stake in shares of Repligen by 113.4% during the third quarter. Blue Trust Inc. now owns 239 shares of the biotechnology company’s stock worth $36,000 after purchasing an additional 127 shares during the period. 97.64% of the stock is owned by institutional investors and hedge funds. Repligen Stock Performance Shares of Repligen stock opened at $142.58 on Friday. The firm has a market cap of $7.99 billion, a price-to-earnings ratio of -385.34, a price-to-earnings-growth ratio of 4.27 and a beta of 0.96. The stock’s 50-day moving average is $140.26 and its 200-day moving average is $143.44. Repligen Co. has a one year low of $113.50 and a one year high of $211.13. The company has a debt-to-equity ratio of 0.26, a current ratio of 10.44 and a quick ratio of 5.56. Analyst Ratings Changes A number of equities research analysts recently commented on the company. Wolfe Research initiated coverage on Repligen in a research note on Thursday, November 14th. They set a “peer perform” rating for the company. Stephens reiterated an “overweight” rating and set a $170.00 target price on shares of Repligen in a report on Tuesday, July 30th. JPMorgan Chase & Co. lifted their target price on Repligen from $190.00 to $200.00 and gave the stock an “overweight” rating in a report on Wednesday, July 31st. UBS Group reduced their target price on Repligen from $205.00 to $185.00 and set a “buy” rating on the stock in a report on Wednesday, July 31st. Finally, Royal Bank of Canada reiterated an “outperform” rating and set a $205.00 target price on shares of Repligen in a report on Thursday, September 26th. Four analysts have rated the stock with a hold rating and eight have issued a buy rating to the company’s stock. Based on data from MarketBeat, the stock has a consensus rating of “Moderate Buy” and an average price target of $190.25. Read Our Latest Stock Report on RGEN Insider Activity at Repligen In related news, Director Anthony Hunt sold 22,191 shares of Repligen stock in a transaction dated Tuesday, September 10th. The stock was sold at an average price of $145.37, for a total value of $3,225,905.67. Following the sale, the director now owns 139,840 shares of the company’s stock, valued at approximately $20,328,540.80. The trade was a 13.70 % decrease in their ownership of the stock. The transaction was disclosed in a legal filing with the Securities & Exchange Commission, which can be accessed through the SEC website . 1.20% of the stock is owned by company insiders. Repligen Company Profile ( Free Report ) Repligen Corporation develops and commercializes bioprocessing technologies and systems for use in biological drug manufacturing process in North America, Europe, the Asia Pacific, and internationally. It offers Protein A ligands that are the binding components of Protein A affinity chromatography resins; and cell culture growth factor products. Featured Stories Want to see what other hedge funds are holding RGEN? Visit HoldingsChannel.com to get the latest 13F filings and insider trades for Repligen Co. ( NASDAQ:RGEN – Free Report ). Receive News & Ratings for Repligen Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Repligen and related companies with MarketBeat.com's FREE daily email newsletter .

IT and banking played a pivotal role in capping losses and driving the recovery in the benchmark. Broader indices also edged higher, with gains ranging between 0.9 per cent and 1.8 per cent Mumbai: Domestic stock markets are expected react, when it opens on Monday,to the recent election outcomes in Jharkhand and Maharashtra as well as domestic macroeconomic data and foreign Institutional fund flows, according to the market analysts. The market analysts say that the bi-monthly Monetary Policy Committee (MPC) which will take place in the first week of December will also have an impact of the activities of the investors, as analysts anticipate a 25-bps rate cut amid concerns of slowing economic growth and moderating inflation. The last trading session in the market ended with decent gains, offering relief after weeks of correction.Despite a negative bias for most of the week due to persistent FII selling, Friday's sharp recovery, led by bargain hunting in index heavyweights, helped indices close near their highs. The Nifty and Sensex gained nearly 2 per cent, ending at 23,907.20 and 79,117.10, respectively."Markets will first react to the outcomes of the Maharashtra and Jharkhand elections. Additionally, macroeconomic indicators, including GDP and infrastructure output, will garner significant attention. Participants remain focused on FII fund flows, given their ongoing selling spree," said Ajit Mishra, SVP, Research, Religare Broking Ltd."Looking ahead, the RBI's meeting from December 4th-6th is generating significant interest, with analysts anticipating a 25-bps rate cut amid concerns of slowing economic growth and moderating inflation," said Manish Goel, Founder and MD, Equentis observing the markets. Goel further added that the upcoming week is likely to bring heightened volatility and cautious trading as investors navigate political uncertainties, economic data releases, and corporate developments.Observing the mood of the market, Joseph Thomas, Head of Research, Emkay Wealth Management stated that despite the up seen in the market during the trading sessions, it remains to be seen to what extent the current momentum is going to be sustained next week."The Russia-Ukraine conflict, the Middle East situation which is still awaiting resolution, local election results in crucial states etc. are all factors that may have some impact on the markets in the coming wee," he added. Market experts are hopeful despite the high volatility in the markets, as Krishna Appala, Sr. Research Analyst, Capitalmind Research said, " Despite global challenges, India's long-term growth story remains compelling."Most sectors, except energy, contributed to the rebound, with realty, auto, and FMCG leading the pack. IT and banking played a pivotal role in capping losses and driving the recovery in the benchmark. Broader indices also edged higher, with gains ranging between 0.9 per cent and 1.8 per cent. On the other hand, the foreign investors extended their selling spree in Indian equity markets for the third consecutive week in November, according to data released by the National Stock Exchange. This week alone, foreign investors sold equities worth Rs 11,412 crore, adding to the ongoing selling pressure.With this, the net selling by foreign investors in November has reached Rs 41,872 crores, indicating persistent bearish sentiment from overseas players. The consistent outflow has weighed on market sentiments, creating volatility in the indices. Meanwhile, domestic institutional investors (DIIs) have continued to provide much-needed support to the Indian markets.This week, DIIs purchased equities worth Rs 11,035 crore, cushioning the impact of foreign outflows. Their total net buying in November now stands at Rs 37,559 crore. Stay informed on all the latest news , real-time breaking news updates, and follow all the important headlines in india news and world News on Zee News.This article was generated by an automated content engine and was reviewed by a human editor prior to publication. For additional information, read Elevai Labs’s 8K filing here . Elevai Labs Company Profile ( Get Free Report ) Elevai Labs, Inc, a skincare development company, designs, manufactures, and markets skincare products. Its products include Empower and Enfinity post-skincare procedure care serums for the face, neck, and upper chest regions. The company was formerly known as Reactive Medical Labs Inc and changed its name to Elevai Labs, Inc in December 2021. See Also“It will be Supriya Sule for the Centre and Ajit Pawar for the State. This is what Baramati has decided. That’s why, Supriya tai (elder sister) won during Lok Sabha, and Ajit Pawar will win in the State Assembly election,” a Baramati city resident had told The Hindu just days before the State Assembly election. On November 23, when the counting ended, Ajit Pawar was declared victorious against his nephew, Yugendra Pawar, by a massive margin of 1,00,899 votes. The margin, though lower than in the previous election, is significant this time due to the political situation in the State, where several candidates have won or lost by very narrow margins. In many ways, the margin indicates a decisive mandate by the people of Baramati, the home bastion of the Pawars in the sugar-rich belt of western Maharashtra for decades now. It is also important as the entire Pawar family, including Ajit Pawar’s brother Shrinivas Pawar, and the politically inactive Pratibha Pawar (Nationalist Congress Party founder Sharad Pawar’s wife), had hit the ground to campaign against him. In fact, Mr. Sharad Pawar had fielded Mr. Ajit Pawar’s nephew Yugendra Pawar against him. So, Mr. Ajit Pawar’s success has personal and political significance. On Sunday (November 24, 2024), Mr. Sharad Pawar said that the Baramati result had been anticipated. Mr. Yugendra Pawar told The Hindu that it had always been an uphill fight. The strategists in Mr. Ajit Pawar’s team heaved a sigh of relief after the success of their plan against a veteran of Maharashtra politics, Mr. Sharad Pawar, in a constituency where unfavourable reports on Mr. Ajit Pawar were seen till the Lok Sabha election. They decoded the secret behind the success of seven-term MLA Mr. Ajit Pawar, who has now won his eighth term from the Pawar family bastion, at a time everyone from the Pawar family, including his own brother, had campaigned against him. Behind the victory was a meticulous strategy put in place by a core team of loyalists, after microscopically studying the constituency, both at a community level, as well as at the level of the constituent village. Separate manifestos were put in place for each village, and for each community group, highlighting the work done by Mr. Ajit Pawar over his long tenure, and what he promised to do once voted to power. Mr. Ajit Pawar has been representing Baramati for seven straight terms now. He has never seen defeat here. This is his eighth term as the Baramati MLA. Another important strategy was the assessment of the reasons for a backlash during the Lok Sabha election, and working on the image building aspect, particularly among a few communities, including the Scheduled Castes and the Muslims. “Additionally, we made sure that the 20,000 outstation voters came to Baramati to vote that day. If it had been a close fight, these 20,000 votes would have played a decisive role. The booth committee workers were activated to take the work of Ajit Pawar till the last voter,” Kiran Gujar, a close aide and strategist for Mr. Ajit Pawar, said. With respect to the discontentment against the non-performing local leadership that was perceived to be close to Mr. Ajit Pawar, they were moved aside, and Mr. Ajit Pawar himself communicated this to the electorate. “This helped people believe that ‘Dada’ lives by his word,” a Mahayuti leader said. It further helped the latter that Mr. Sharad Pawar did not express a negative opinion about Mr. Ajit Pawar in the last rally held in Baramati on November 18, a party leader said. Muslim voters choose “There are 117 villages. There are 1,000 votes in each village. We targeted them. Moreover, 70% of the Muslim community voted for ‘Dada’. We showcased how ‘Dada’ had done work worth ₹65 crore for them. In the last election, only 10% [Muslims] had voted for us. So this was a clear gain,” a Mahayuti leader said. The younger generation chose Mr. Ajit Pawar over Mr. Yugendra Pawar, Mr. Gujar said. When contacted, Mr. Yugendra Pawar told The Hindu that he was still assessing the reasons for his defeat. “This trend was seen in the entire State. Stalwarts didn’t make it. To go up against someone like Ajit Pawar was not easy. But we have to stand for what we believe in, our ideology. He has been in power for 30-35 years. So we knew this was difficult. Does it mean that you just give up? We used to think that there is a wave for tutari (trumpet, the NCP-SP election symbol), that the MVA will come to power. I am young and new. I can again start from scratch and rebuild everything. Up-down goes on. Didn’t desert anyone, stayed loyal. It is surprising; lot of good, intelligent, clean people have lost,” Mr. Yugendra Pawar said. Published - November 24, 2024 10:33 pm IST Copy link Email Facebook Twitter Telegram LinkedIn WhatsApp Reddit Maharashtra / Maharashtra Assembly Elections 2024 / India / election

London: For all the rousing revelry and festive fizz that Christmas Day can bring, for some it only ramps up the confusion and anxiety. Older relatives may find it more of a slog to host than they are used to; if they are the guests, a lively new setting can compound the feelings of bewilderment and grumpiness. But when do signs of stress actually signify something more serious? Elizabeth Leonard, 58, recalls how a few years ago, her previously capable, cheerful mother, then aged 71, had an uncharacteristic outburst a few days before Christmas – picking a fight when normally she would do anything to avoid confrontation. On Christmas Day itself she said she couldn’t cook the turkey because there was something wrong with the oven. Elizabeth took over the cooking and found it was working perfectly. It marked the beginning of a long road to accepting that there might be something wrong, followed eventually by a diagnosis of dementia. A Christmas meal disaster could be a clue. Credit: Getty Images/iStockphoto “It’s a time for making memories, but it’s often during Christmas that we realise that something isn’t quite right with someone,” says Simon Wheeler, a senior knowledge officer at the Alzheimer’s Society. “At first it may seem like a momentary lapse – perhaps just a sign of getting old – but after a while you start to become concerned.” Different types of dementia can cause varying symptoms – from memory loss to difficulty with everyday tasks – that can often be picked up on in a social setting. The most common kind of dementia is Alzheimer’s (early symptoms include confusion and short-term memory problems), followed by vascular dementia (problems with planning and concentration) and Lewy bodies dementia (this includes Parkinson’s dementia, difficulty focusing and delusions). Some symptoms, such as memory loss, are common to many dementias – especially in the early stages. Here’s what to look out for and what to do if you’re worried about a relative this Christmas. Forgetfulness Forgetfulness, as a symptom of dementia, generally applies to short-term memory. “People might be able to sit there and talk about Christmas 10 years ago and remember all the details,” says Angelo Makri, also a senior knowledge officer at the Alzheimer’s Society. “But if you ask them what they did yesterday and they can’t answer, that’s where you know [there may be a problem]“, as well as forgetting people’s names, or their relationship with someone; for example a nephew or niece that they haven’t seen for a year. Of course, as we get older, it is normal to experience an element of memory lapse – so when should you worry? “It will be things that are out of character for that person. With dementia, it is progressive and so can affect daily living. Loading “The person that forgets to put the turkey in the oven, or burns the turkey, may be forgetting to put the oven on for dinner every day.” Repeating questions “As with memory loss, this is quite consistent across all types of dementia and it can happen quite early,” says Makri. “Someone might ask a question over and over again, and it gets to a point where you realise they’re not retaining this information. It’s quite upsetting to witness.” Wheeler adds: “The first noticeable sign of Alzheimer’s disease is typically failing episodic memory. This is when a person has trouble encoding new memories of events and is caused by damage to regions of the brain called the hippocampus and the entorhinal cortex. “It’s declining episodic memory that causes the ‘saying the same thing, over and over’ symptom because the person doesn’t recall having said it previously. They never stored the memory in the first place so it doesn’t inform their future thoughts and actions.” Difficulties in carrying out old family traditions may hint at difficulties with daily tasks. Credit: Getty Images Difficulty carrying out familiar daily tasks While a complex matter like making a whole Christmas dinner would be enough to confuse a lot of us, there may be a problem if someone has difficulty carrying out one familiar job. “For example, if the same person always does the stuffing every year and then they forget to bring the ingredients, or they forget the process of how to do it. People will begin to have difficulty remembering the process of something, or planning, or concentrating.” Difficulty with tech “Confusion with technology is not, of course, specific to people living with dementia,” says Wheeler. “However, people with dementia can – and do – struggle with technology. “As their condition deteriorates over time, their brain will increasingly struggle to process information and think clearly, meaning that technologies that were once easy to use and navigate, for example a mobile phone or a laptop, may become increasingly difficult to use.” Time spent at end-of-year celebrations can bring comfort to the elderly and also a greater understanding of where they are at. Credit: Tribune Difficulty following a conversation “People can have difficulty finding the right word, or just following the thread of a conversation.” says Makri. “They might take longer to process the information they’ve heard, or they might just not be communicating very much. Sometimes they will become a bit withdrawn. They retreat slightly because, actually, they can’t follow the thread of the conversation any more.” Wheeler adds that although people with vascular dementia may not have problems with memory at first, in the context of a conversation they may easily lose the thread, either because they get distracted, they get overwhelmed by too much information, or because their working memory – the ability to keep a thought in your head for a few seconds or more – isn’t working as well as it used to. Spatial and temporal awareness This can be a symptom of all types of dementia. “Sometimes people might be confused about the time or the place,” says Makri. “They might not realise whose house they’re in, or not remember where the loo is. They might know it’s Christmas because they’re sitting at a Christmas table with a turkey in front of them, but they might not remember what year it is.” Difficulty controlling emotions The key is whether their behaviour is out of character. “If this is someone who’s always got really angry or anxious about politics, then you might not worry. But if this is someone who doesn’t normally react this way at that point, if they’re suddenly having mood swings and having difficulty controlling their emotions, then this might be an early sign [of some forms of dementia].” People with vascular dementia in particular tend to be more prone to mood problems as well as fatigue, and difficulty concentrating. Inappropriate behaviour This is more of a problem with frontotemporal dementia, a less common type of dementia that involves degeneration in the frontal or temporal lobes of the brain. Early symptoms include changes in personality and behaviour, and/or language difficulties. “You may find a person becomes less inhibited; they might suddenly start saying or doing inappropriate things,” says Makri. Being suddenly suspicious Although this isn’t present with Alzheimer’s, vascular or many other types of dementia, Lewy body dementia – a broad term which includes ‘dementia with Lewy bodies’ and Parkinson’s dementia – can cause delusional beliefs or hallucinations. “Having incorrect beliefs could potentially be an early symptom,” Makri explains. “At that point it’s generally quite mild, but certainly saying something like ‘the neighbours keep having a go at me’, or having a suspicion that the neighbours are talking about them,” could be a sign that something is amiss. What should you do next? Firstly, how much should you worry? “Many of the early symptoms can be caused by other things,” says Makri. “We always say you can’t make a diagnosis at the dinner table. But if someone is presenting with a lot of these symptoms it is a good idea for them to speak to the GP.” The GP will generally carry out tests to rule out other causes, including thyroid deficiencies, urinary tract infection (UTIs) and vitamin B12 deficiency, which can all cause confusion. But how to broach the topic sensitively? Makri suggests that, after speaking to other people who were present, to nominate one close family member to bring this up with the person in question. It’s also helpful to keep notes of the symptoms. MRI brain scans showing different dementia types. Credit: Boston University Ideally, the person themselves will go to the GP, who may then follow up with a referral to a memory clinic and possibly a brain scan. If the person is in denial – which can itself be a part of dementia – a family member can ring the GP and pass on their concerns, and while the GP won’t be able to comment because of patient confidentiality, they may be able to follow up with the patient. The Telegraph, London Save Log in , register or subscribe to save articles for later. Dementia Christmas UK For subscribers Illness Family Most Viewed in World LoadingNAPLES, Fla. – Akshay Bhatia and Jennifer Kupcho met for the first time at a cocktail party on Tuesday at the Grant Thornton Invitational. The mixed-team partners didn’t see each other again until they warmed up next to each other on the range Friday. With tournament pro-ams scheduled on Wednesday and Thursday, there’s not much time to build team chemistry. “Jennifer and I were texting yesterday trying to figure out like a team name,” said Bhatia. “That didn't work.” The newness of it all, however, did nothing to dampen their success. Kupcho and Bhatia opened with a 13-under 59 at Tiburon Golf Club in the scramble format to sit one shot behind former UCLA players Patty Tavatanakit and Jake Knapp, who also met for the first time this week. While this marks the second playing of the Grant Thornton Invitational, there aren’t many repeat teams from last year. In fact, of the 16 total teams, only three played together last year, including defending champions Lydia Ko and Jason Day. Canadians Brooke Henderson and Corey Conners, who finished second in 2024, and Lexi Thompson/Rickie Fowler round out the trio of returners. “You know, you just don't want it to be awkward,” said Bhatia of teeing it up with a well-known stranger. Cameron Young and Lauren Coughlin met for the first time on Monday and had dinner together on Thursday evening. They hadn’t played a round of golf together until Friday’s opening round, but Young knew of Coughlin's breakout season on the LPGA. “It was a scramble, so we figured one of us would hit one good shot,” said Coughlin of the day’s strategy. Things are bound to get more complicated on Saturday, however, when the format changes to foursomes (alternate shot). When asked what they learned about each other’s games on Day 1, Coughlin said, “He hits it really far and really straight.” Young noted that he made Coughlin putt all the three- and five-footers first on Friday. “Really nice kind of just leaning on my putter over there and watching her make those,” he said. France’s Celine Boutier and Matthieu Pavon met for the first time at the Paris Olympics. Boutier arrived at the venue early to watch Pavon hit the first tee shot and was in shock by how many people were there. Pavon had never felt more emotional inside the ropes than he did that day. The Grant Thornton provides a rare opportunity for the two compatriots to get to know each other. “This is why I feel like it's a great tournament because I'm not sharing a lot of time during the year with Celine,” said Pavon, “and she's probably the best player ever in France. She won a major, she had a very, very successful career so far. It's all about like watching what she's got and what she does better than most other players, and that's very nice for me.” As for the leaders, well, they met on Tuesday for a practice round. Tavatanakit had planned to only play nine holes but had so much fun with Knapp that she carried on after the turn. “I feel like I haven't played golf like this free in a while,” said Tavatanakit, “so it is actually a really nice feeling. I feel very secure out there because I know I have a really good partner.” The pair birdied every hole on the front nine to shoot 27. On the back, they finished eagle-birdie to post a 58 on a windy day in south Florida. Their team name – Rocco’s on Thursday – is an ode to a favorite bar in Westwood. Last week, Knapp spent some time with another Bruin, Solheim Cup player Alison Lee, and got some insight on his new partner. “She said she can get a little upset at times and get down on herself maybe,” said Knapp of what he learned, “so she was like just don't let her get that way. I was like, that's fine, I get upset, too. “No, it was just kind of more so just like keep the conversation going and just make sure we have a good time between shots.” “Basically, he's just babysitting me,” Tavatanakit replied with a smile. The banter is already flowing.

Beyoncé trolls Netflix over buffering issues ahead of NFL Christmas Gameday halftime showThe first commercial batch of made-in-Canada low-carbon aviation fuel sourced from non-food grade canola and tallow has been produced and quickly purchased. Fuel retailer Parkland Corp. said Tuesday it has successfully produced about 100,000 litres of the fuel at its refinery in Burnaby, B.C. “using existing infrastructure.” Parkland senior vice-president Ferio Pugliese said it means production can easily be scaled up, but only if Canada provides the necessary conditions to create an ecosystem around the nascent commodity and its adoption across the country. “We need to do more to make low-carbon air travel a reality,” Pugliese said during the announcement in Vancouver on Tuesday. “We need a long-term Canadian solution for low-carbon, sustainable aviation fuel.” While the potential for emission reduction is massive with production in Canada is also significantly more expensive, Pugliese said. He notes that similar low-carbon fuels used in vehicles, buses and ferries have about one-eighth of the carbon content when compared to traditional fuels. Pugliese said other countries such as the United States incentivize production and use of low-carbon jet fuel, creating the necessary ecosystem to support a local industry. “Currently, the Canadian aviation industry purchases low-carbon aviation (fuel) from other countries and imports it from across the globe into Canada. That makes little sense.” Parkland began trying to develop the fuel in 2017, and the entire batch of the first production run has already been bought by Air Canada. Pugliese said the purchase of the fuel by Air Canada completes a value chain within the country that shows local development, production, sale and use of low-carbon jet fuel can be achieved to the benefit of everyone — but only if the support from government is there. “Airlines need very practical solutions, and today, right here in B.C., Parkland has created a made-in-Canada solution to a global challenge,” he said. The comments echoed that of WestJet CEO Alexis von Hoensbroech, who in 2023 said the global push for decarbonizing commercial aviation by 2050 will cause spikes in airfares unless governments intervene. Part of the challenge, von Hoensbroech said, is that alternative energy sources such as electric or hydrogen aircraft remains a long way from reality, making the sector difficult to decarbonize. In February, a pair of industry groups, including the National Airlines Council of Canada, said the country needed incentives matching that of the United States to spark production of sustainable aviation fuels. Commercial aviation giant Airbus has said that low-carbon jet fuel can reduce carbon-dioxide emissions by about 80 per cent, and development is ongoing for planes to be able to run completely on it instead of needing to mix it with conventional fuels. But Airbus also said the ecosystem for the fuel is still “in its infancy,” with just 600 million litres produced last year, making up 0.2 per cent of all aviation fuel for 2023. “Appropriate regulatory mechanisms and inventive structures still need to be put in place, and even then, there are challenges associated with the limited availability of land and biowaste,” Airbus said of the technology on its website. Airbus has said it is increasing its own use of low-carbon fuels with a goal of reaching 30 per cent of its total fuel mix by 2030.

Syria's new transitional prime minister on Tuesday said it was time for "stability and calm" in the country, two days after longtime president Bashar al-Assad was toppled by rebels in a lightning offensive. The rebels appointed Mohammad al-Bashir as the transitional head of government to run the country until March 1, a statement said. US Secretary of State Antony Blinken urged all nations to support an "inclusive" political process in Syria, saying the United States would eventually recognise a government if it meets such standards. "Now it is time for this people to enjoy stability and calm," Bashir told Qatar's Al Jazeera television in his first interview since being appointed. A senior official told US broadcaster NBC that Assad was in Moscow, after he fled Syria as an Islamist-led rebel alliance swept into Damascus on Sunday, ending five decades of brutal rule by his clan. Abu Mohammed al-Jolani, the Islamist leader who headed the rebel offensive, had announced talks on a transfer of power and vowed to pursue former senior officials responsible for torture and war crimes. Jolani on Tuesday sought to allay fears over how Syria would be ruled, telling British broadcaster Sky News that Syria was "exhausted" by war and would not be heading back into one. "Syria will be rebuilt... The country is moving towards development and reconstruction. It's going towards stability," he said. "People are exhausted from war. So the country isn't ready for another one and it's not going to get into another one." His group, Hayat Tahrir al-Sham, is rooted in Syria's Al-Qaeda branch and is proscribed by many Western governments as a terrorist organisation, though it has sought to moderate its image. Blinken said the future government of Syria should be "credible, inclusive and non-sectarian". Laying out US priorities, Blinken said the new government must "uphold clear commitments to fully respect the rights of minorities" and allow the flow of humanitarian assistance. The United States wanted the next government to "prevent Syria from being used as a base for terrorism", he added. Although they no longer hold any territory in Syria, the jihadists of the Islamic State group remain active. The Syrian Observatory for Human Rights war monitor said IS fighters killed 54 government troops after capturing them as they fled across the vast Syrian desert. The UN envoy for Syria said the groups that forced Assad to flee must transform their "good messages" into actions on the ground. "They have been sending messages of unity, of inclusiveness," Geir Pedersen said. "What we need not to see is... that this is not followed up in practice in the days and the weeks ahead of us," he added. EU foreign policy chief Kaja Kallas warned of the risks of sectarian violence and a resurgence of extremism. "We must avoid a repeat of the horrific scenarios in Iraq, Libya and Afghanistan." Syria's nearly 14-year civil war killed 500,000 people and forced half the country to flee their homes, millions of them finding refuge abroad. Jolani, who now uses his real name Ahmed al-Sharaa, vowed: "We will not hesitate to hold accountable the criminals, murderers, security and army officers involved in torturing the Syrian people." More from this section The fall of Assad has sparked a frantic search by families of the tens of thousands of people held in his security services' jails and detention centres. As they advanced towards Damascus, the rebels released thousands of detainees, but many more remain missing. Syria's White Helmet rescuers on Tuesday called on Russia to pressure Assad into providing maps of secret jails and lists of detainees as they race against time to release prisoners. A large crowd gathered Monday outside Saydnaya jail, synonymous with the worst atrocities of Assad's rule, to search for relatives, many of whom had spent years in captivity, AFP correspondents reported. "I'm looking for my brother, who has been missing since 2013. We've looked everywhere for him, we think he's here, in Saydnaya," said 52-year-old Umm Walid. Crowds of freed prisoners wandered the streets of Damascus, many maimed by torture, weakened by illness and emaciated by hunger. The United Nations said whoever ended up in power in Syria must hold Assad and his lieutenants to account. UN investigators who for years have been gathering evidence of horrific crimes called Assad's ouster a "game-changer" because they will now be able to access "the crime scene". While Syrians were celebrating Assad's ouster, the country now faces enormous uncertainty, and it is unclear whether the dreams of democracy so many sacrificed their lives for will be realised. Further complicating prospects, the Israeli military said it had conducted hundreds of strikes on Syria over the past two days. Pedersen, the UN special envoy for Syria, called on Israel to stop. "We are continuing to see Israeli movements and bombardments into Syrian territory. This needs to stop," he said. But Israeli Prime Minister Benjamin Netanyahu warned Syria's new rulers that he would respond "forcefully" if they allow "Iran to re-establish itself in Syria, or permits the transfer of Iranian weapons or any other weapons to Hezbollah". Lebanon's Hezbollah meanwhile said it hoped that Syria's new rulers would "take a firm stand against Israeli occupation, while preventing foreign interference in its affairs". The Britain-based Observatory said Israeli strikes had "destroyed the most important military sites in Syria". The monitor said the strikes targeted weapons depots, naval vessels and a research centre that Western governments suspected of having links to chemical weapons production. Israel, which borders Syria, also sent troops into the UN-patrolled buffer zone east of the Israeli-annexed Golan Heights. Israel backer the United States said the incursion must be "temporary", after the United Nations said Israel was violating the 1974 armistice. The Israeli defence minister said the military had orders to "establish a sterile defence zone free of weapons and terrorist threats in southern Syria, without a permanent Israeli presence." bur-ser/jsa/NBA urges players to take precautions after thieves target homes of Wolves' Conley, Bucks' Portis

North America's top professional sports leagues have issued warnings to their players about a growing threat from high-tech, organized burglary rings, whose tools of choice are passports, cutting-edge technology and a 90-day calendar. The NBA memo, citing FBI intelligence, specifically linked the crimes to "transnational South American Theft Groups" that target "professional athletes and other high-net-worth individuals." These groups are known for using "advanced techniques" such as pre-surveillance, drones, signal-jamming devices and other cutting-edge technology. The NFL highlighted the risks posed by what it called "organized and skilled groups" of burglars targeting wealthy athletes. While the warnings did not name victims, they were issued after the homes of athletes including Kansas City Chiefs stars Patrick Mahomes and Travis Kelce and Milwaukee Bucks forward Bobby Portis were recently burglarized. The tactics described in the memos bear a striking resemblance to a wave of break-ins targeting affluent residents in Southern California. Federal and local officials from Los Angeles and Orange County have reported a spike in break-ins by what they call "burglary tourists" — criminals from Central and South America who legally enter the U.S. on 90-day tourist visas under the Electronic System for Travel Authorization (ESTA). But instead of packing swimsuits... Andrew Blankstein and David K. Li | NBC News

EFL stadium set to be invaded by Greek ultras armed with flares... weeks after shocking vandalism following Euro clashTransMedics Group, Inc. ( NASDAQ:TMDX – Get Free Report ) traded down 5% on Friday . The company traded as low as $72.68 and last traded at $75.39. 748,139 shares were traded during mid-day trading, a decline of 24% from the average session volume of 982,771 shares. The stock had previously closed at $79.34. Analyst Upgrades and Downgrades A number of analysts recently commented on the company. Needham & Company LLC reaffirmed a “hold” rating and set a $109.00 price objective on shares of TransMedics Group in a research note on Friday. Canaccord Genuity Group decreased their price target on shares of TransMedics Group from $109.00 to $104.00 and set a “buy” rating on the stock in a research note on Wednesday. Oppenheimer cut their price objective on shares of TransMedics Group from $200.00 to $125.00 and set an “outperform” rating for the company in a research report on Tuesday, October 29th. Stephens raised their target price on shares of TransMedics Group from $151.00 to $178.00 and gave the stock an “overweight” rating in a research report on Friday, August 2nd. Finally, Robert W. Baird lowered their target price on shares of TransMedics Group from $200.00 to $150.00 and set an “outperform” rating for the company in a research note on Tuesday, October 29th. Two analysts have rated the stock with a hold rating, eight have assigned a buy rating and one has assigned a strong buy rating to the stock. According to MarketBeat.com, the stock has a consensus rating of “Moderate Buy” and a consensus price target of $131.80. Check Out Our Latest Stock Analysis on TMDX TransMedics Group Stock Performance TransMedics Group ( NASDAQ:TMDX – Get Free Report ) last issued its earnings results on Monday, October 28th. The company reported $0.12 earnings per share for the quarter, missing the consensus estimate of $0.29 by ($0.17). TransMedics Group had a return on equity of 18.74% and a net margin of 8.14%. The firm had revenue of $108.76 million during the quarter, compared to analysts’ expectations of $115.00 million. During the same period last year, the business posted ($0.12) earnings per share. The company’s quarterly revenue was up 63.7% compared to the same quarter last year. Equities research analysts anticipate that TransMedics Group, Inc. will post 1 EPS for the current year. Insider Activity In related news, insider Tamer I. Khayal sold 2,958 shares of the stock in a transaction on Tuesday, October 1st. The stock was sold at an average price of $148.24, for a total value of $438,493.92. Following the completion of the sale, the insider now directly owns 20,843 shares in the company, valued at approximately $3,089,766.32. This represents a 12.43 % decrease in their position. The sale was disclosed in a document filed with the Securities & Exchange Commission, which is accessible through the SEC website . Also, insider Nicholas Corcoran sold 10,000 shares of the business’s stock in a transaction dated Tuesday, August 27th. The stock was sold at an average price of $176.02, for a total value of $1,760,200.00. Following the transaction, the insider now owns 21,105 shares in the company, valued at approximately $3,714,902.10. This represents a 32.15 % decrease in their position. The disclosure for this sale can be found here . Insiders have sold 36,958 shares of company stock valued at $5,230,528 in the last three months. Corporate insiders own 7.00% of the company’s stock. Institutional Investors Weigh In On TransMedics Group Hedge funds have recently modified their holdings of the stock. Vaughan Nelson Investment Management L.P. purchased a new position in TransMedics Group in the 2nd quarter worth approximately $39,862,000. Driehaus Capital Management LLC raised its stake in shares of TransMedics Group by 15.8% during the second quarter. Driehaus Capital Management LLC now owns 1,486,073 shares of the company’s stock valued at $223,832,000 after purchasing an additional 202,867 shares during the period. Principal Financial Group Inc. lifted its position in shares of TransMedics Group by 260.1% during the third quarter. Principal Financial Group Inc. now owns 202,287 shares of the company’s stock worth $31,759,000 after purchasing an additional 146,115 shares in the last quarter. Hood River Capital Management LLC purchased a new position in shares of TransMedics Group in the second quarter valued at $18,854,000. Finally, Canada Pension Plan Investment Board acquired a new stake in TransMedics Group during the 2nd quarter valued at $16,086,000. 99.67% of the stock is currently owned by hedge funds and other institutional investors. TransMedics Group Company Profile ( Get Free Report ) TransMedics Group, Inc, a commercial-stage medical technology company, engages in transforming organ transplant therapy for end-stage organ failure patients in the United States and internationally. The company offers Organ Care System (OCS), a portable organ perfusion, optimization, and monitoring system that utilizes its proprietary and customized technology to replicate near-physiologic conditions for donor organs outside of the human body. Featured Articles Receive News & Ratings for TransMedics Group Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for TransMedics Group and related companies with MarketBeat.com's FREE daily email newsletter .

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