SAN ANTONIO, Texas (AP) — Zach Calzada threw for 182 yards and his 17-yard scoring pass to Roy Alexander was the game's only touchdown and Incarnate Word beat Villanova 13-6 on Saturday in the second round of the FCS playoffs. The Cardinals (11-2), who earned their highest seed in program history at No. 6, travel to face third-seeded South Dakota State in the quarterfinals. Brack Peacock kicked a 23-yard field goal to give the Cardinals a 3-0 lead with 8:48 before halftime. Villanova (10-4) tied it on 49-yard field goal by Ethan Gettman almost five minutes later. Late in the third, Gettman gave the Wildcats their lone lead when he kicked a 52-yarder. Calzada connected with Roy early in the fourth and Peacock added insurance in the last stanza with a 35 yarder with 4:14 remaining. Lontrell Turner had 120 yards rushing on 18 carries for Incarnate Word. Connor Watkins threw for 103 yards and an interception for Villanova whose offense was outgained 437-138. The Wildcats hadn't been kept out of the end zone since Nov. 5, 2022 when Towson beat Villanova 27-3. Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-football

JERUSALEM (AP) — Israel approved a United States-brokered ceasefire agreement with Lebanon's Hezbollah on Tuesday, setting the stage for an end to nearly 14 months of fighting linked to the ongoing war in the Gaza Strip. Israeli warplanes meanwhile carried out the most intense wave of strikes in Beirut and its southern suburbs since the start of the conflict and issued a record number of evacuation warnings. At least 24 people were killed in strikes across the country, according to local authorities, as Israel signaled it aims to keep pummeling Hezbollah before the ceasefire is set to take hold at 4 a.m. local time on Wednesday. Another huge airstrike shook Beirut shortly after the ceasefire was announced. Israel's security Cabinet approved the ceasefire agreement late Tuesday after it was presented by Prime Minister Benjamin Netanyahu, his office said. U.S. President Joe Biden, speaking in Washington, called the agreement “good news” and said his administration would make a renewed push for a ceasefire in Gaza. An Israel-Hezbollah ceasefire would mark the first major step toward ending the regionwide unrest triggered by Hamas’ attack on Israel on Oct. 7, 2023. But it does not address the devastating war in Gaza, where Hamas is still holding dozens of hostages and the conflict is more intractable. U.S. President-elect Donald Trump has vowed to bring peace to the Middle East without saying how. The Biden administration spent much of this year trying to broker a ceasefire and hostage release in Gaza but the talks repeatedly sputtered to a halt . Still, any halt to the fighting in Lebanon is expected to reduce the likelihood of war between Israel and Iran, which backs both Hezbollah and Hamas and exchanged direct fire with Israel on two occasions earlier this year. Netanyahu presented the ceasefire proposal to Cabinet ministers after a televised address in which he listed a series of accomplishments against Israel’s enemies across the region. He said a ceasefire with Hezbollah would further isolate Hamas in Gaza and allow Israel to focus on its main enemy, Iran, which backs both groups. “If Hezbollah breaks the agreement and tries to rearm, we will attack,” he said. “For every violation, we will attack with might.” The ceasefire deal calls for a two-month initial halt in fighting and would require Hezbollah to end its armed presence in a broad swath of southern Lebanon, while Israeli troops would return to their side of the border. Thousands of additional Lebanese troops and U.N. peacekeepers would deploy in the south, and an international panel headed by the United States would monitor all sides’ compliance. But implementation remains a major question mark. Israel has demanded the right to act should Hezbollah violate its obligations. Lebanese officials have rejected writing that into the proposal. Biden said Israel reserved the right to quickly resume operations in Lebanon if Hezbollah breaks the terms of the truce, but that the deal "was designed to be a permanent cessation of hostilities.” Netanyahu’s office said Israel appreciated the U.S. efforts in securing the deal but “reserves the right to act against every threat to its security.” Hezbollah has said it accepts the proposal, but a senior official with the group said Tuesday that it had not seen the agreement in its final form. “After reviewing the agreement signed by the enemy government, we will see if there is a match between what we stated and what was agreed upon by the Lebanese officials,” Mahmoud Qamati, deputy chair of Hezbollah’s political council, told the Al Jazeera news network. “We want an end to the aggression, of course, but not at the expense of the sovereignty of the state.” of Lebanon, he said. “Any violation of sovereignty is refused.” Even as Israeli, U.S, Lebanese and international officials have expressed growing optimism over a ceasefire, Israel has continued its campaign in Lebanon, which it says aims to cripple Hezbollah’s military capabilities. An Israeli strike on Tuesday leveled a residential building in the central Beirut district of Basta — the second time in recent days warplanes have hit the crowded area near the city’s downtown. At least seven people were killed and 37 wounded, according to Lebanon's Health Ministry. Strikes on Beirut's southern suburbs killed at least one person and wounded 13, it said. Three people were killed in a separate strike in Beirut and three in a strike on a Palestinian refugee camp in southern Lebanon. Lebanese state media said another 10 people were killed in the eastern Baalbek province. Israel says it targets Hezbollah fighters and their infrastructure. Israel also struck a building in Beirut's bustling commercial district of Hamra for the first time, hitting a site that is around 400 meters (yards) from Lebanon’s Central Bank. There were no reports of casualties. The Israeli military said it struck targets in Beirut and other areas linked to Hezbollah's financial arm. The evacuation warnings covered many areas, including parts of Beirut that previously have not been targeted. The warnings, coupled with fear that Israel was ratcheting up attacks before a ceasefire, sent residents fleeing. Traffic was gridlocked, and some cars had mattresses tied to them. Dozens of people, some wearing their pajamas, gathered in a central square, huddling under blankets or standing around fires as Israeli drones buzzed loudly overhead. Hezbollah, meanwhile, kept up its rocket fire, triggering air raid sirens across northern Israel. Israeli military spokesman Avichay Adraee issued evacuation warnings for 20 buildings in Beirut's southern suburbs, where Hezbollah has a major presence, as well as a warning for the southern town of Naqoura where the U.N. peacekeeping mission, UNIFIL, is headquartered. UNIFIL spokesperson Andrea Tenenti told The Associated Press that peacekeepers will not evacuate. The Israeli military also said its ground troops clashed with Hezbollah forces and destroyed rocket launchers in the Slouqi area on the eastern end of the Litani River, a few kilometers (miles) from the Israeli border. Under the ceasefire deal, Hezbollah would be required to move its forces north of the Litani, which in some places is about 30 kilometers (20 miles) north of the border. Hezbollah began firing into northern Israel, saying it was showing support for the Palestinians, a day after Hamas carried out its Oct. 7, 2023, attack on southern Israel, triggering the Gaza war. Israel returned fire on Hezbollah, and the two sides have been exchanging barrages ever since. Israel escalated its campaign of bombardment in mid-September and later sent troops into Lebanon, vowing to put an end to Hezbollah fire so tens of thousands of evacuated Israelis could return to their homes. More than 3,760 people have been killed by Israeli fire in Lebanon the past 13 months, many of them civilians, according to Lebanese health officials. The bombardment has driven 1.2 million people from their homes. Israel says it has killed more than 2,000 Hezbollah members. Hezbollah fire has forced some 50,000 Israelis to evacuate in the country’s north, and its rockets have reached as far south in Israel as Tel Aviv. At least 75 people have been killed, more than half of them civilians. More than 50 Israeli soldiers have died in the ground offensive in Lebanon. Chehayeb and Mroue reported from Beirut. Associated Press reporters Lujain Jo and Sally Abou AlJoud in Beirut, and Aamer Madhani in Washington, contributed. Find more of AP’s war coverage at https://apnews.com/hub/israel-hamas-warCommanders' Jayden Daniels Breaks Robert Griffin III's NFL Rookie QB Rushing Record

When Dr. Kemi Wijesundera moved into the new Telus Health family medicine clinic in downtown Toronto, he quickly found he had one less thing to worry about during consults. Each of the seven examination rooms in the modern new clinic, which Telus Health has opened under its “MyCare” brand, is equipped with “AI scribe” software that listens to appointments (with patients’ consent) and uses artificial intelligence to summarize the conversations in the standardized medical note form. Before the patient even gets out the door, the notes from their appointment, including their medical history, as well as any requisitions, prescriptions and special instructions from their doctor, are uploaded to their phone through the Telus MyCare app. “This is the future of health care,” says Wijesundera, a recent medical school grad and one of six family physicians at the new Telus Health MyCare Union clinic. Located in repurposed office space on York Street, just south of Union Station, the “digital first” clinic, which had a soft launch in late summer, is now fully operational. 516 Estimated number of Torontonians without a family doctor 2.5 Estimated number of Ontarians without a family doctor 6.5 Estimated number of Canadians without a family doctor Source: Ontario College of Family Physicians, Ontario Community Health Profiles Partnership, OurCare Initiative Toronto Star graphic Located in repurposed office space on York Street, just south of Union Station, the “digital first” clinic, which had a soft launch in late summer, is now fully operational and facing a unique challenge: at a time when an 516,000 Torontonians are looking for a family doctor, the physicians at the clinic are looking for patients — up to 6,000 of them. “It gives people who live in the Toronto area a new way to become attached to a family doctor within the public health-care system,” says Chris Engst, vice-president of consumer health for Telus Health, which opened its first two MyCare clinics in Victoria and Vancouver in 2020. The expansion is part of a broader, global trend that’s seeing private companies taking ownership stakes in the provision of medical services, an area many investors see as ripe with opportunity as wait-lists for family doctors and certain surgical procedures remain stubbornly high. Unlike its main telecom competitors, Rogers Communications and BCE, which have diversified into sports team and media ownership, Telus is staking a claim on health care. In 2022, it , formerly Morneau Shepell, for $2.3 billion, as well as buying up a substantial share of the market for electronic medical record (EMR) software in Canada over the last decade. After these and other acquisitions, Telus says it now provides health-care services to some 76 million people in more than 160 countries. “It’s a regular family practice. The physicians are doing everything from preventative care, immunizations, chronic disease management, acute care, whatever the care needs are of their patients,” says Dr. Alissia Valentinis, a family doctor and medical director of the Toronto MyCare clinic. 1 Estimated number of Torontonians who could be without a family doctor by 2026 4.4 Estimated number of Ontarians who could be without a family doctor by 2026 Source: Ontario College of Family Physicians, INSPIRE-Primary Health Care Toronto Star graphic Dr. Alissia Valentinis, medical director of the Telus Health MyCare Union clinic, explains that the MyCare model is similar to other private clinics where doctors pay a percentage of their provincial billings to the company running the clinic to cover rent, staff and insurance. In this case, Telus Health manages the clinic while the physicians are independent contractors who are “100 per cent publicly funded.” “It’s a regular family practice. The physicians are doing everything from preventative care, immunizations, chronic disease management, acute care, whatever the care needs are of their patients,” says Valentinis. One thing the new Toronto MyCare clinic isn’t: a cramped and stuffy space in a lowrise office complex that some may associate with more traditional medical offices. A wall covered with plants about six metres long that stretches to the ceiling greets patients in the clinic’s waiting room on the second floor of Telus Harbour, a 30-storey, LEED Platinum office building next to Scotiabank Arena. Floor-to-ceiling windows that look down on York Street illuminate the seven, gleaming-white examination rooms that are equipped with two computer screens, one for virtual consultations and one for medical charting. One slightly larger examination room can accommodate minor procedures, such as the removal of lumps or bumps. A counselling room featuring cushioned seats offers a quiet space for doctors to have difficult conversations with patients, if necessary, or for breastfeeding moms to find some privacy. A team of clinical operations support staff assist physicians with administration, pharmacy inquiries, referrals and appointment bookings. “We’ve been using technology to try and think about, how do you deliver primary care in a unique way which helps to support the needs of patients and also helps to support the needs of the clinicians who work with us?” says Engst. A key pillar in this quest is the Telus Health MyCare app, a sort of all-in-one platform that not only holds MyCare patients’ electronic medical records, but also allows patients to book same-day or next-day appointments and see physicians at the Union clinic virtually or in-person. Despite the obvious value for patients in a city starved of family doctors like Toronto, the company’s expansion into the health-care space has not been without controversy. A living wall of plants about six metres long that stretches to the ceiling greets patients in the clinic’s waiting room on the second floor of Telus Harbour, a 30-storey, LEED Platinum office building next to Scotiabank Arena. A few years ago, Telus Health opened but then closed the doors of a family medicine clinic in downtown Toronto, a move it said was a “strategic decision” to “re-evaluate and refine our approach to supporting health-care needs in Toronto.” “This period of reflection and analysis led to the development and launch of the Telus Health MyCare Union clinic,” the company said in an email. “This new model represents an evolution of our initial concept, incorporating lessons learned and aligning more closely with our goal of improving access to primary care for thousands of Toronto residents.” In late 2022, British Columbia’s Medical Services Commission, responsible for that province’s public health insurance system, went to court seeking an injunction against a separate Telus Health program, called LifePlus, that the government alleged charged patients thousands of dollars a year for care already covered publicly — an illegal practice under the B.C. Medicare Protection Act. In April 2023, the commission and Telus Health reached an agreement and clarified processes to better distinguish insured from uninsured services, the company said. It’s unclear how much, if any, profit Telus is making on the Toronto MyCare clinic, but Engst did say its physicians bill the provincial health system just like any other public health-care clinician, with a portion of those fees going to cover support staff and overhead. A less tangible benefit for the company could be a treasure trove of potentially valuable data. And that has not gone unnoticed by privacy and public health-care advocates, who question what the Vancouver-based company is doing with its now vast holdings of personal health information. “Telus owns most of the electronic medical record (EMR) software market in Canada, including the EMR that I use. All of my prescribing information is in my EMR. Where is the data going and are they monetizing it for secondary use?” says Danielle Martin, chair of the Department of Family and Community Medicine at the University of Toronto. Danielle Martin, chair of the Department of Family and Community Medicine at the University of Toronto, says that while the MyCare Union clinic “is what every doctor and every patient wants and deserves” when it comes to physicians being able to focus on being clinicians instead of running an office, she questions why a private company is stepping in to meet demand instead of the public health-care system. Engst says Telus Health, as both a technology and health-care company, “brings unique capabilities to improve health-care delivery and access.” “To be clear, the Telus Health MyCare Union clinic supports the public health-care system by providing access to publicly insured services,” he added. Martin notes that the province already funds models similar to the MyCare clinics through family health teams and community health centres, but these interprofessional teams — which include not only doctors, but also nurses, social workers, dietitians and pharmacists — only cover about 30 per cent of the population. “This is what creates a market for Telus, because doctors prefer to work in an environment like that and patients prefer to get care in an environment like that,” says Martin, who is also a family doctor. But she questions what Telus Health does with the patient data it retains. “Telus owns most of the electronic medical record (EMR) software market in Canada, including the EMR that I use. All of my prescribing information is in my EMR. Where is the data going and are they monetizing it for secondary use?” Martin says. In an email, Telus Health said it does not sell any data collected by its virtual-care platforms, including MyCare, and is “deeply committed” to the internationally recognized Privacy By Design principles. Privacy by Design, created by Ontario’s former privacy commissioner Ann Cavoukian, is a system based on seven principles intended to proactively embed privacy into information technology and business systems. “All data collected from our services are treated as personal health information and handled in accordance with the rigorous laws and best practices applicable to personal health information,” the company said. 19 Estimated number of hours per week family doctors spend on administrative work Source: Ontario Medical Association Toronto Star graphic Back at the MyCare Union clinic, Wijesundera says the technology deployed by Telus Health is what made working at the clinic attractive as a new medical grad who wants to spend more time seeing patients and less time doing paperwork. “This is potentially going to solve physician burnout,” he says. The Ontario Medical Association reports that family doctors spend about 19 hours per week on administrative tasks, such as writing notes or filling in patient forms. “I get more time to look at the patient, have a conversation and it’s not just me on the computer typing. It’s a nice interaction. The patients feel heard as well.”None

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ANDERSON, S.C. — Lamont Burks Jr. likely didn’t know that police were tracking his movement through South Carolina earlier this week, but a piece of technology used by law enforcement is what brought him into custody. Wanted for first-degree murder in Sioux Falls, Burks Jr. was apprehended by the Anderson County Sheriff’s Office in northwestern South Carolina on Tuesday, Nov. 19. ADVERTISEMENT “I can confirm his license plate did pass by a stationary license plate reader in Anderson County,” ACSO Public Information Officer Carrie Miller told Sioux Falls Live. “This notified deputies in the area to look for his car as it was associated with a murder in South Dakota.” Burks Jr. was wanted in connection to a deadly shooting in Sioux Falls’ Dunham Park in late August. When a fight broke out between a large group of people. The fight led to gunshots from at least two different firearms, killing one person and injuring three more. After an 11-week investigation, a grand jury in Minnehaha County indicted 32-year-old Walter Stewart and Burks Jr., 28. Stewart was located by police in Sioux Falls and arrested, but Burks Jr.’s whereabouts were unknown. That was until he passed by an automatic license plate reader in South Carolina, which notified law enforcement there. According to Flock, a company that manufactures ALPRs, the cameras scan license plates that pass by them, adding them into a database accessible to law enforcement agencies. South Carolina news outlets report that the cameras in the Palmetto State capture roughly 400 million license plate numbers from more than 4 million vehicles that travel the state each year. While police spokesman Sam Clemens confirmed that Sioux Falls does not have ALPRs installed in the city, the City of Madison implemented the use of ALPRs in 2022. ADVERTISEMENT According to Flock’s transparency portal, Madison’s 27 ALPRs scanned nearly 45,000 license plates in the past 30 days, registering 478 hits on National Crime Information Center and Amber Alert databases. The policy with the Madison Police Department, however, requires human verification of any hit from either database before action is taken. The cameras are also not equipped with facial recognition or traffic enforcement tools. Nine months after they were installed in Madison, Chief of Police Justin Meyer told Keloland News in 2023 that the ALPRs had already helped apprehend suspects in a variety of cases, ranging from local thefts to stolen vehicles. “They are proven assets at this point in time, and I don’t know that we could go back to running without them,” Meyer said. In an email to Sioux Falls Live, Flock said it could not provide a list of jurisdictions in South Dakota that have ALPRs installed, saying the company doesn’t have “a reliable list.” While the concept of ALPRs seems simple, the practice has been widely scrutinized throughout the nation. Various lawsuits challenge the legality and the scope, questioning law enforcement’s probable cause when capturing the data, as well as how much data is being collected. In South Carolina, where Burks Jr. was apprehended, Democratic state Rep. Todd Rutherford has worked for years on a bill that would better regulate who can access ALPR data and why, arguing that the lack of regulation allows law enforcement to track citizens who aren’t committing crimes. ADVERTISEMENT “They collect information about your license tag, which seems innocuous until you realize it’s kind of like the data in your cellphone, that you didn’t realize was so important,” Rutherford said in a March hearing of the South Carolina Legislature. “If Princess Kate was living in South Carolina, specifically in Florence, it would not be hard for people to have figured out that she was suffering from a disease because we could track her car to an oncologist using license plate readers.” Law enforcement agencies across the country, however, say the ALPRs create a more proactive approach to solving crime and have helped put criminals in jail. Since ALPRs led to the arrest of Burks Jr., he’s been l odged at the Anderson County Jail awaiting extradition to South Dakota. Officials in Anderson County say it’s up to the Sioux Falls Police Department to arrange a time to move Burks Jr., but that it could take longer if Burks Jr. decides to fight the extradition. Court dates in Minnehaha County have not yet been established for Burks Jr. If convicted of first-degree murder, he faces a minimum sentence of life in prison and a maximum sentence of death. Stewart, who is also charged with first-degree murder, is expected to appear in court on Nov. 25.When Katja Vogt considers a Jaguar, she pictures a British-made car purring confidently along the Italian coastline — a vision of familiarity that conveys "that dreaming, longing feeling we all love." She's not sure what to think about Jaguar now after the 89-year-old company announced a radical rebranding that featured loud colors and androgynous people — but no cars. Jaguar, the company says, will now be JaGUar. It will produce only electric vehicles beginning in 2026. Bad attention is good attention, Jaguar execs would appear to believe. The car brand has prompted mockery online for posting a glitzy ad without a single car in it. Say goodbye to British racing green, Cotswold Blue and black. Its colors are henceforth electric pink, red and yellow, according to a video that sparked backlash online. Its mission statement: "Create exuberance. Live vivid. Delete ordinary. Break moulds." "Intrigued?" @Jaguar posted on social media. "Weird and unsettled" is more like it, Vogt wrote on Instagram. "Especially now, with the world feeling so dystopian," the Cyprus-based brand designer wrote, "a heritage brand like Jaguar should be conveying feelings of safety, stability, and maybe a hint of rebellion — the kind that shakes things up in a good way, not in a way that unsettles." Our brands, ourselves Jaguar was one of several iconic companies that announced significant rebrandings in recent weeks, upending a series of commercial — and cultural — landmarks by which many modern human beings sort one another, carve out identities and recognize the world around them. Campbell's, the 155-year-old American icon that artist Andy Warhol immortalized in pop culture decades ago, is ready for a new, soupless name. Comcast's corporate reorganization means there will soon be two television networks with "NBC" in their name — CNBC and MSNBC — that will no longer have any corporate connection to NBC News, a U.S. legacy news outlet. CNBC One could even argue the United States itself is rebranding with the election of former President Donald Trump and Republican majorities in the House and Senate. Unlike Trump's first election in 2016, he won the popular vote in what many called a national referendum on American identity. Are we, then, the sum total of our consumer decisions — what we buy, where we travel and whom we elect? Certainly, it's a question for those privileged enough to be able to afford such choices. Volumes of research in the art and science of branding — from "brandr," an old Norse word for burning symbols into the hides of livestock — say those factors do contribute to the modern sense of identity. So rebranding, especially of heritage names, can be a deeply felt affront to consumers. "It can feel like the brand is turning its back on everything that it stood for — and therefore it feels like it's turning its back on us, the people who subscribe to that idea or ideology," said Ali Marmaduke, strategy director with the Amsterdam-based Brand Potential. He said cultural tension — polarization — is surging over politics, wars in Russia and the Mideast, the environment, public health and more, creating what Marmaduke said is known as a "polycrisis": the idea that there are several massive crises converging that feel scary and complex. Campbell's soups "People are understandably freaked out by that," he said. "So we are looking for something that will help us navigate this changing, threatening world that we face." Trump's "Make America Great Again" qualifies. So did President Joe Biden's "Build Back Better" slogan. Campbell's soup itself — "Mmm Mmm Good" — isn't going anywhere, CEO Mark Clouse said. The company's new name, Campbell's Co., will reflect "the full breadth of our portfolio," which includes brands like Prego pasta sauce and Goldfish crackers. What is Jaguar? None of the recent activity around heritage brands sparked a backlash as ferocious as Jaguar's. The company stood as a pillar of tradition-loving British identity since World War II. The famous "leaper" cat Jaguar logo is pictured in 2019 at the Auto show in Paris, France. Jaguar said its approach to the rebrand was rooted in the philosophy of its founder, Sir William Lyons, to "copy nothing." What it's calling "the new Jaguar" will overhaul everything from the font of its name to the positioning of it's famous "leaper" cat. "Exuberant modernism" will "define all aspects of the new Jaguar world," according to the news release. The approach is thought to be aimed at selling fewer cars at a six-figure price point to a more diverse customer base. The reaction ranged from bewilderment to hostility. Memes sprouted up likening the video to the Teletubbies, a Benetton ad and — perhaps predictably — a bow to "woke" culture as the blowback intersected with politics. Be the first to know

Advance Auto Parts to close hundreds of stores, shut down West Coast operationsNEW YORK (AP) — Stocks are closing lower as Wall Street ends a holiday-shortened week on a down note. The S&P 500 fell 1.1% Friday and the the Dow Jones Industrial Average lost 333 points, or 0.8%. The Nasdaq composite dropped 1.5%. The “Magnificent 7” stocks weighed on the market, led by declines in Nvidia, Tesla and Microsoft. Even with the loss, the S&P 500 had a modest gain for the week and is still headed for its second consecutive annual gain of more than 20%, the first time that has happened since 1997-1998. The yield on the 10-year Treasury rose to 4.62%. THIS IS A BREAKING NEWS UPDATE. AP’s earlier story follows below. NEW YORK (AP) — Technology stocks are dragging down the market Friday as Wall Street closes out a holiday-shortened week. The S&P 500 fell 1.3%, with more than 90% of stocks in the benchmark index losing ground. The benchmark index was managing to hold onto a modest gain for the week. The Dow Jones Industrial Average fell 418 points, or 1%, to 42,878 as of 1:43 p.m. Eastern time. The Nasdaq composite fell 1.8%. Technology stocks were the biggest weight on the market Friday. Semiconductor giant Nvidia slumped 2.7%. Its enormous valuation gives it an outsize influence on indexes. Other Big Tech stocks losing ground included Microsoft, with a 2% decline. A wide range of retailers also fell. Amazon fell 1.9% and Best Buy slipped 1.8%. The sector is being closely watched for clues on how it performed during the holiday shopping season. Energy stocks held up better than the rest of the market, with a loss of just 0.1% as crude oil prices rose 1.4%. The S&P 500 gained nearly 3% over a 3-day stretch before breaking for the Christmas holiday. On Thursday, the index posted a small decline. “There's just some uncertainty over this relief rally we've witnessed since last week,” said Adam Turnquist, chief technical strategist for LPL Financial. Despite Friday's drop, the market is moving closer to another standout annual finish . The S&P 500 is on track for a gain of around 25% in 2024. That would mark a second consecutive yearly gain of more than 20%, the first time that has happened since 1997-1998. The gains have been driven partly by upbeat economic data showing that consumers continued spending and the labor market remained strong. Inflation, while still high, has also been steadily easing. A report on Friday showed that sales and inventory estimates for the wholesales trade industry fell 0.2% in November, following a slight gain in October. That weaker-than-expected report follows an update on the labor market Thursday that showed unemployment benefits held steady last week. The stream of upbeat economic data and easing inflation helped prompt a reversal in the Federal Reserve's interest rate policy this year. Expectations for interest rate cuts also helped drive market gains. The central bank recently delivered its third cut to interest rates in 2024. Even though Inflation has come closer to the central bank's target of 2%, it remains stubbornly above that mark and worries about it heating up again have tempered the forecast for more interest rate cuts. Inflation concerns have added to uncertainties heading into 2025, which include the labor market’s path ahead and shifting economic policies under incoming President Donald Trump. Worries have risen that Trump’s preference for tariffs and other policies could lead to higher inflation , a bigger U.S. government debt and difficulties for global trade. Amedisys rose 4.7% after the home health care and hospice services provider agreed to extend the deadline for its sale to UnitedHealth Group. The Justice Department had sued to block the $3.3 billion deal, citing concerns he combination would hinder access to home health and hospice services in the U.S. The move to extend the deadline comes ahead of an expected shift in regulatory policy under Trump. The incoming administration is expected to have a more permissive approach to dealmaking and is less likely to raise antitrust concerns. In Asia, Japan’s benchmark index surged as the yen remained weak against the dollar. Stocks in South Korea fell after the main opposition party voted to impeach the country’s acting leader. Markets in Europe gained ground. Bond yields held relatively steady. The yield on the 10-year Treasury rose to 4.61% from 4.59% late Thursday. The yield on the two-year Treasury slipped to 4.31% from 4.33% late Thursday. Wall Street will have more economic updates to look forward to next week, including reports on pending home sales and home prices. There will also be reports on U.S. construction spending and snapshots of manufacturing activity. Damian J. Troise, The Associated Press

Couple charged in ring suspected of stealing $1 million in Lululemon clothesGrog dopeys So, the thrashing meted out by Ireland to the Flying Fijians last weekend was the referee’s fault! Again. Any wins by the Flying Fijians are never the referee’s fault. How much of a Third World mentality and pathetic are the grog dopeys of Fiji? When will Fijians stop blaming everyone else? I guess wrecking the RFNS Puamau was also the referee’s fault and the fact that the people and government in the country are useless is also the referee’s fault. JAN NISSAR, Sydney, Australia. FNPF contributions Can the Government please reconsider the re-entry of people that had no options but to withdraw totally. On the first occasion I withdrew to help my parents pay for my wedding. On the second occasion I had to withdraw for my mother’s medical expenses. For the past 16 years I have been working but despite making several requests I have been told I cannot rejoin. My reasons were genuine. Please can I rejoin for the rest of my working life which could be anything between 6-10years? TAI SMITH, Nasinu Secondary School Rd, Kinoya, Nasinu Family reunions It has always been my policy to refrain from engaging in debate with overseas correspondents, like me, who are not resident in Fiji. Fiji Times readers, I feel are more interested in domestic affairs instead of slanging matches between offshore letter writers. Yesterday’s letter (FT 25/11) from Jan Nissar though, screams for a response. He asks: “Why was there such great pomp, ceremony and celebration? Is there something wrong with living in Fiji?”, when writing of the departure of PALM workers family members. All of this above a tag line of J.N. Sydney, Australia! After years of separation while striving to increase their family life style, these families now look forward to a better future. Yes Jan, they have won the lottery. They are coming to join you. Who did you vote for? TERRY HULME, Australia Milky water, stench Who is responsible for the enforcement of regulations for the very milky water and the unbearable stench present in the Yarawa Rd creek in the Raiwasa area in Suva? The Suva City Council, Ministry of Environment, and the Water Authority of Fiji have been approached and responded but the problem is still there. Who should we approach now? ASISH VINAY PRASAD, Park Rd, Raiwasa, Suva Transport payment The truck/carrier operators on Ovalau are infuriated regarding the much delayed RSL Education Transport Payment. Such an issue was not experienced during the term of the previous government. If there was a delay, it would take only a few days for the MOE to effect payments, unlike now. Payments are long outstanding, not for weeks but months and numerous calls to those responsible at MOE have proven futile. One wonders, were the payment funds diverted to cater for the 50-plus COP29 group expenses or to cater for Government’s weekly globetrotting or for their soqo and kalavata? A service has been provided and payment is long overdue. What’s happening? Who’s responsible for such a “botched up mess?” ANTHONY SAHAI, Levuka, Ovalau RFNS Timo I hope our Fiji Navy sailors don’t have the misconception that the new RFNS Timo is a landing craft and try crossing over a reef. Sobo! WISE MUAVONO, Balawa, Lautoka FNPF pensions Although I am grateful that Parmesh Chand has publicly acknowledged that what was done to us FNPF pensioners in 2012 was wrong while under his chairmanship of the FNPF Board, I am very disappointed that he took all this time to come out and acknowledge this. Shame on you Mr Chand. ROBERT MANOA, Nasinu 16 Days of Activism! As I flipped through the World Health Organization’s page, my attention was drawn to the wealth of information presented on the global 16 Days of Activism Against Violence Against Women, which is a key international moment to call for an end to violence against women and girls. It runs from 25th November (the International Day for the Elimination of Violence Against Women) until 10th December (Human Rights Day). WHO shared that violence against women happens in every country and culture, causing harm to millions of women and girls. WHO added that around the world today, prolonged and intense conflicts have resulted in a continuous rise in of all forms of gender-based violence. I salute WHO for playing an active role in strengthening health systems and for calling all parties to respect their obligations under international humanitarian and human rights law to protect women and girls from gender-based violence and ensure access to essential health services. Activists marched in Labasa town on Monday during the launch of the 16 Days of Activism against Gender-Based Violence. They were in high spirits, making every effort to end violence against girls and women. Our ‘iron-lady’ Shamima Ali is spearheading this campaign, and alongside her, women and girls need our support! RAJNESH ISHWAR LINGAM, Nadawa, Nasinu. Drunkards in town West Police SP Lakobo Vaisewa’s stern warning of arresting disorderly drunkards has had negligible effect as groups of unruly people continue to consume alcoholic beverages in plain view of the public. Police patrols are rare whenever there is a drinking assembly within the city boundaries, despite the Lautoka Police Station located just metres away from all the drinking hotspots. Just last week, while on my usual early morning walk, I observed a lone police officer armed with a police baton nonchalantly approaching a drinking party consisting of rowdy teens at the Pacific Energy Service Station premises (a very common drinking base) situated across the Vomo St junction. Assuming that the lawman would dutifully confront and detain these hooligans for public drinking and disturbing the peace, I was shocked to see this officer informally conversing with these drunkards and shaking hands with them. After the pleasantries were exchanged followed by a kaila, the police officer casually strolled away, leaving the drunks to continue their alcohol binge. I wonder if the situation would have been any different if the guilty party belonged to a different ethnicity, since the two-tier law and justice system is quite dominant in our communities. Law enforcement officers are generally expected to maintain the law, especially in cases of public disturbances or recurring issues like public drinking. When officers appear to be lenient or indifferent to such behaviour, it destabilises the rule of law and often leads to a loss of confidence in the police force. With such lack of commitment to enforcing the law, no wonder the Men in Blue continually gets a bad rapport. NISHANT SINGH,Lautoka Suffering in Baku I believe that the way the Assistant Minister for Women has described the suffering of the Fiji delegation to COP29 in Baku, Azerbaijan one would have thought they travelled there on the back of camels in a caravan through an unforgiving desert in the year 1524 (not 2024) without food, water and medicines to reach Baku. It appears they are the only delegation who have stayed away from their families, missed meals and the usual comforts of life at home, suffered from cold and wet, flu and blisters. We all know that people living in Fiji never miss a meal. No other delegates have suffered these things. I have always known that Fijians are resilient and hardworking people who seem to have been allocated tents in Baku while all the other delegates from the developed world travelled by modern jetliners and are staying in luxury hotels and have a lot of money and help. I do not know about anyone else, but I feel for the suffering of the Fiji delegation and the sacrifices they are making for us, for a better Fiji and a better world! I am genuinely concerned about their treacherous camel ride back to Fiji. Are they strong enough to make it back safely? We all should appreciate the hard work they are doing and not be sceptical or critical. I do not for a second believe that the Assistant Minister is being a drama queen. JAN NISSAR, Sydney, Australia The ban IF the Tui Namosi has decided to ban land owners or the people of Namosi caught for their involvement in drugs, then perhaps it will be even-handed for him to also banish thieves, sex perpetrators, domestic abuses etc., from the province. Anyway, I wonder if Ratu Matanitobua was literally better advised or has sought guidance from a legal counsel before giving out his command? Fiji Human Rights and Anti-Discrimination Commission, I hope you have not looked away from the issue! AREKI DAWAI, Suva. GCC use by date Like Nishant Singh of Lautoka (F/T Nov22) and other writers to this column the GCC has already expired their “use by date” and should be abolished. Former prime minister Bainimarama did the right thing by banishing them under that famous mango tree. They should have been left alone to continue to enjoy themselves under the tree. What good has the GCC ever done for Fiji? ROBERT MANOA, Nasinu Our schoolies Our local schoolies where do they go? Not to a hotel on an island overseas, but usually to an island home, across our seas. EDWARD BLAKELOCK, Admiral Circle, Pacific Harbour Social media ban It’s the parents who should be banned from using social media, not the children. Children copy what their parents do. If the parents stop wasting family time on social media then so will their children. AREN NUNNINK, Hooper St, Savusavu Failure! A failure on every front: Pacific climate advocates decry COP 29 outcomes (RNZ/ FT 26/11/24). The biggest Pacific Island country Papua New Guinea anticipated well and decided not to send any delegation to COP29 saying it’s a waste of time. Fiji sent a bloated delegation of 56 to what has turned out to be “A failure on every front”. But the people of Fiji remain truly blessed with such profound political leadership. RAJEND NAIDU, Sydney, Australia Optimistic The Coalition Government in New Zealand are optimistic after completing the first year. Can the same be said of our Government? DAN URAI, Lautoka Drugs and coconuts The Fiji Times news on drug in coconuts (FT25/11) will affect the sale to some extent. Travellers stop to quench their thirst by drinking this safe natural drink. We are well blessed in our tropical climate. Such publications may affect Fiji tourism. As I stopped for a green coconut drink the vendor said: “This natural drink is good for health.” TAHIR ALI, Hamilton, New Zealand Pool saga THAT swimming pool, is it still in the pipeline? Oh, I see time to review the pipeline. Mmm! NAVNEET RAM (TD), Lautoka

Baltimore (7-4) at Los Angeles Chargers (7-3) Monday, 8:15 p.m. EST, ESPN/ABC BetMGM NFL odds: Ravens by 3. Against the spread: Ravens 5-5-1; Chargers 7-3. Series record: Ravens lead 9-5. Last meeting: Ravens beat Chargers 20-10 in Inglewood, Calif., on Nov. 26, 2023. Last week: Ravens lost to Pittsburgh 18-16; Chargers beat Cincinnati 34-27. Ravens offense: overall (1), rush (2), pass (3), scoring (2). Ravens defense: overall (3), rush (26), pass (2), scoring (23). Chargers offense: overall (18), rush (12), pass (19), scoring (18). Chargers defense: overall (11), rush (11), pass (12), scoring (1). Turnover differential: Ravens plus-2; Chargers plus-8. K Justin Tucker missed two field goals last week and is under pressure after spending most of his career beyond reproach. He’s missed six field goals on the season and is 4 for 12 from 50-plus yards since the start of last season. WR Ladd McConkey had a career-high 123 yards on six receptions against Cincinnati. The rookie came up with clutch catches of 28 and 27 yards to set up the game-winning touchdown. Chargers RB J.K. Dobbins vs. Ravens’ run defense. Dobbins showed promise during his time in Baltimore, but he never was able to live up to that potential because of injuries. Now in Los Angeles on a one-year “prove it” contract, Dobbins has nearly matched his most productive season as a professional with 726 yards and eight touchdowns in 10 games. After seeing Pittsburgh run the ball 34 times last week, the Chargers will be glad to copy that bruising approach with Dobbins. The Ravens are allowing 77.5 rushing yards per game, but even the sturdiest defense can buckle against that volume of work, so getting off the field will be critical. Baltimore’s defense has a couple of significant injury concerns. LB Roquan Smith (hamstring) left last weekend’s game, and S Kyle Hamilton has been nursing an ankle problem, although he played against the Steelers. ... Chargers OLB Khalil Mack (groin) didn’t play against Cincinnati. If the veteran pass rusher remains out this week, it would be a big loss to the chances of containing the Ravens' multi-faceted offense. The Ravens have won four straight over the Chargers in the regular season, but Los Angeles did earn a 23-17 AFC wild-card round upset in January 2019. ... Baltimore cruised to a 34-6 win over the Chargers in its first visit to SoFi Stadium on Oct. 17, 2021. Ravens RB Derrick Henry leads the NFL with 1,185 yards rushing and 15 total TDs (13 rushing and two receiving). He’s also run for a league-high 52 first downs. ... Henry is one rushing TD shy of the Ravens’ single-season record, set by Jamal Lewis in 2003. ... Baltimore QB Lamar Jackson is 6-2 on “Monday Night Football” with 20 TD passes and no interceptions. ... Henry is one of four players in the Super Bowl era to score a TD in each of the first 11 games of a season. The others are O.J. Simpson (1975), John Riggins (1983) and Jerry Rice (1987). ... The Ravens have scored touchdowns on a league-best 77.8% of their red zone trips. ... Jackson needs 124 yards passing and 16 yards rushing for a second consecutive season with 3,000 passing and 600 rushing. Since the AFL-NFL merger, only Randall Cunningham (1988-1990), Cam Newton (2011-12), Josh Allen (2021-22) and Jalen Hurts (2021-23) have accomplished that feat. ... Dobbins ran for two touchdowns against Cincinnati, giving him multiple scores in two of his past three games. He did it twice in 24 games as a Raven. ... OLB Tuli Tuipulotu had 1 1/2 sacks of Bengals QB Joe Burrow, his third straight game with more than one. All seven of Tuipulotu’s sacks this season have come in the past four games, and six of his eight tackles for loss have come in that span. ... The Chargers allowed a season-worst 27 points to Cincinnati after holding each of their previous nine opponents to 20 points or fewer. ... QB Justin Herbert has thrown one interception in 277 attempts this season. That lone pick came in Week 2 at Carolina. ... The Chargers lost their fifth turnover of the season when Herbert fumbled to start the fourth quarter. It was their first turnover at home. ... Los Angeles does not have a takeaway in its past two games. Herbert has heated up after a slow start in terms of fantasy production, having thrown for multiple touchdowns in three of his past four games. He is likely to keep that success going this week. Baltimore has allowed 22 scores through the air, which is tied with Houston for second most in the league, and Herbert should have plenty of chances to add to that total in what could be another high-scoring matchup. AP NFL: https://apnews.com/hub/NFL

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Stock market today: S&P 500, Dow notch fresh records as Wall Street shrugs off Trump's tariff threatST. PAUL, Minn. (AP) — Josh Norris broke a tie on a power play with 7:18 left, Leevi Merilainen made 30 saves in his fifth NHL game and the Ottawa Senators beat the Minnesota Wild 3-1 on Sunday night. Ottawa has won seven of its past nine games, while the Wild have lost five of their past seven. The Senators won in Minnesota for the first time since 2016. With starter Linus Ullmark and backup Anton Forsberg out with injuries, the Senators have been relying on Merilainen and Mads Sogaard since before the NHL holiday break. Frederick Gaudreau opened the scoring for Minnesota late in the first period. Ridly Greig tied it early in the second. Claude Giroux added an empty-netter. Takeaways Senators: A team that finds itself surprisingly in a playoff position after missing the postseason the past six seasons topped a Western Conference contender in Minnesota. Norris has been a big part of the Senators' surge and now ranks second on the team with 14 goals. Wild: A lower-body injury kept Kirill Kaprizov out of his second straight game, but Joel Eriksson Ek returned after missing 11 games with a lower-body injury. The Wild are 17-5-4 with Eriksson Ek in the lineup and 5-6-0 without him. Key moment The Wild killed one penalty midway through the third, but Jared Spurgeon went to the box seconds later on a holding call. Norris scored on the power play. Up next The Senators’ nine-game trip continues Thursday at Dallas night. The Wild host Nashville on Tuesday night. ___ AP NHL: Phil Ervin, The Associated PressSolid Tumor Testing Market to Grow at 5.9% CAGR, Projected to Hit USD 36.48 Billion by 2028 11-26-2024 09:40 PM CET | Business, Economy, Finances, Banking & Insurance Press release from: Data Bridge Market Research (DBMR) / PR Agency: Data Bridge Market Research (DBMR) The Solid Tumor Testing Market sector is undergoing significant transformation, with substantial growth and technological advancements expected by 2031. According to a new in-depth market research report, the sector is poised for expansion, driven by various factors such as market size, share, and emerging trends. This comprehensive report provides key insights into the Solid Tumor Testing market, exploring critical market segmentation and definitions. It highlights the essential components driving growth, offering a clear picture of the industry's trajectory. Utilizing SWOT and PESTEL analyses, the report evaluates the market's strengths, weaknesses, opportunities, and threats, while also considering political, economic, social, technological, environmental, and legal factors that impact the market landscape. The study offers valuable insights into the competitive landscape, highlighting recent developments and geographical distribution across key regions. Expert competitor analysis provides a detailed understanding of market dynamics, offering strategic guidance for businesses and investors. With robust analysis and future projections, this report serves as a vital resource for stakeholders looking to capitalize on emerging opportunities and navigate challenges in the Solid Tumor Testing market. What is the projected market size & growth rate of the Solid Tumor Testing Market? Market Analysis and Insights : Global Solid Tumor Testing Market The solid tumor testing market is expected to witness market growth at a rate of 5.90% in the forecast period of 2021 to 2028, and is estimated to reach the value of USD 36,481.64 million by 2028. Data Bridge Market Research report on solid tumor testing market provides analysis and insights regarding the various factors expected to be prevalent throughout the forecast period while providing their impacts on the market's growth. The rapid advancements in the healthcare sector globally is escalating the growth of solid tumor testing market. Solid tumor testing refers to a procedure that is utilized for evaluating primary tumor and determining extent/location of any metastases. This type of testing allows effective treatment options to be considered in order to avoid the spread of cancerous cells. The rise in the number of people suffering from cancer across the globe acts as one of the major factors driving the growth of solid tumor testing market. The high utilization of spatial techniques for cancer research and diagnosis, and introduction of novel technologies for minimizing errors accelerate the market growth. The increase in number of establishment of various market players dealing in these technologies, and development of high-throughput, rapid, sensitive, and multi-parametric solutions for prognosis, diagnostics, and treatment further influence the market. Additionally, increase in investments, grants and funds, rise in population, surge in healthcare expenditure and rise in funding support by various organizations positively affects the solid tumor testing market. Furthermore, rise in demand for personalized medicine extend profitable opportunity to the market players in the forecast period of 2021 to 2028. On the other hand, difficulties with approval procedure are expected to obstruct the market growth. The presence of stringent regulations is projected to challenge the solid tumor testing market in the forecast period of 2021-2028. This solid tumor testing market report provides details of new recent developments, trade regulations, import export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on solid tumor testing market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth. Browse Detailed TOC, Tables and Figures with Charts which is spread across 350 Pages that provides exclusive data, information, vital statistics, trends, and competitive landscape details in this niche sector. This research report is the result of an extensive primary and secondary research effort into the Solid Tumor Testing market. It provides a thorough overview of the market's current and future objectives, along with a competitive analysis of the industry, broken down by application, type and regional trends. It also provides a dashboard overview of the past and present performance of leading companies. A variety of methodologies and analyses are used in the research to ensure accurate and comprehensive information about the Solid Tumor Testing Market. Get a Sample PDF of Report - https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-solid-tumor-testing-market Which are the driving factors of the Solid Tumor Testing market? The driving factors of the Solid Tumor Testing market include technological advancements that enhance product efficiency and user experience, increasing consumer demand driven by changing lifestyle preferences, and favorable government regulations and policies that support market growth. Additionally, rising investment in research and development and the expanding application scope of Solid Tumor Testing across various industries further propel market expansion. Solid Tumor Testing Market - Competitive and Segmentation Analysis: Global Solid Tumor Testing Market, By Type (Conventional Testing, Non-Conventional Testing), Cancer Type (Breast Cancer, Lung Cancer, Colorectal Cancer, Prostate Cancer, Cervical Cancer), Application (Clinical, Research), Country (U.S., Canada, Mexico, Germany, Italy, U.K., France, Spain, Netherland, Belgium, Switzerland, Turkey, Russia, Rest of Europe, Japan, China, India, South Korea, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific, Brazil, Argentina, Rest of South America, South Africa, Saudi Arabia, UAE, Egypt, Israel, Rest of Middle East & Africa) Industry Trends and Forecast to 2031 How do you determine the list of the key players included in the report? With the aim of clearly revealing the competitive situation of the industry, we concretely analyze not only the leading enterprises that have a voice on a global scale, but also the regional small and medium-sized companies that play key roles and have plenty of potential growth. Which are the top companies operating in the Solid Tumor Testing market? The major players covered in the solid tumor testing market report are BiovewInc, Aviva Biosciences, Laboratory Corporation of American Holdings (LabCorp), A&G Pharmaceutical, AffymetrixInc, Precision Therapeutics, ThermoFisher Scientific, Siemens, Menarini Silicon Biosystems, Myriad Genetics, Qiagen, Roche, Diadx, EONE- Diagnostics, Genome center, Exosome Sciences, iCellate Medical, Inivata, IV Diagnostics, LCM Genec, Celsee Diagnostics, Gen-Probe Inc, Digene, Quest Diagnostic Inc, and Cancer Genetics Inc, among other domestic and global players. Short Description About Solid Tumor Testing Market: The Global Solid Tumor Testing market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon. North America, especially The United States, will still play an important role which can not be ignored. Any changes from United States might affect the development trend of Solid Tumor Testing. The market in North America is expected to grow considerably during the forecast period. The high adoption of advanced technology and the presence of large players in this region are likely to create ample growth opportunities for the market. Europe also play important roles in global market, with a magnificent growth in CAGR During the Forecast period 2024-2031. Solid Tumor Testing Market size is projected to reach Multimillion USD by 2031, In comparison to 2024, at unexpected CAGR during 2024-2031. Despite the presence of intense competition, due to the global recovery trend is clear, investors are still optimistic about this area, and it will still be more new investments entering the field in the future. This report focuses on the Solid Tumor Testing in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application. Get a Sample Copy of the Solid Tumor Testing Report 2024 What are your main data sources? Both Primary and Secondary data sources are being used while compiling the report. Primary sources include extensive interviews of key opinion leaders and industry experts (such as experienced front-line staff, directors, CEOs, and marketing executives), downstream distributors, as well as end-users. Secondary sources include the research of the annual and financial reports of the top companies, public files, new journals, etc. We also cooperate with some third-party databases. Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historical data and forecast (2024-2031) of the following regions are covered in Chapters What are the key regions in the global Solid Tumor Testing market? North America (United States, Canada and Mexico) Europe (Germany, UK, France, Italy, Russia and Turkey etc.) Asia-Pacific (China, Japan, Korea, India, Australia, Indonesia, Thailand, Philippines, Malaysia and Vietnam) South America (Brazil, Argentina, Columbia etc.) Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa) This Solid Tumor Testing Market Research/Analysis Report Contains Answers to your following Questions What are the global trends in the Solid Tumor Testing market? Would the market witness an increase or decline in the demand in the coming years? What is the estimated demand for different types of products in Solid Tumor Testing? What are the upcoming industry applications and trends for Solid Tumor Testing market? What Are Projections of Global Solid Tumor Testing Industry Considering Capacity, Production and Production Value? What Will Be the Estimation of Cost and Profit? What Will Be Market Share, Supply and Consumption? What about Import and Export? Where will the strategic developments take the industry in the mid to long-term? What are the factors contributing to the final price of Solid Tumor Testing? What are the raw materials used for Solid Tumor Testing manufacturing? How big is the opportunity for the Solid Tumor Testing market? How will the increasing adoption of Solid Tumor Testing for mining impact the growth rate of the overall market? How much is the global Solid Tumor Testing market worth? What was the value of the market In 2020? Who are the major players operating in the Solid Tumor Testing market? Which companies are the front runners? Which are the recent industry trends that can be implemented to generate additional revenue streams? What Should Be Entry Strategies, Countermeasures to Economic Impact, and Marketing Channels for Solid Tumor Testing Industry? Customization of the Report Can I modify the scope of the report and customize it to suit my requirements? Yes. Customized requirements of multi-dimensional, deep-level and high-quality can help our customers precisely grasp market opportunities, effortlessly confront market challenges, properly formulate market strategies and act promptly, thus to win them sufficient time and space for market competition. Detailed TOC of Global Solid Tumor Testing Market Insights and Forecast to 2031 Introduction Market Segmentation Executive Summary Premium Insights Market Overview Solid Tumor Testing Market By Type Solid Tumor Testing Market By Function Solid Tumor Testing Market By Material Solid Tumor Testing Market By End User Solid Tumor Testing Market By Region Solid Tumor Testing Market: Company Landscape SWOT Analysis Company Profiles Continued... https://futureresearchinsight1500.blogspot.com/2024/11/weatherization-services-market-size.html https://futureresearchinsight1500.blogspot.com/2024/11/static-random-access-memory-sram-market.html https://futureresearchinsight1500.blogspot.com/2024/11/prepared-meat-and-seafood-equipment.html Data Bridge Market Research: Today's trends are a great way to predict future events! Data Bridge Market Research is a market research and consulting company that stands out for its innovative and distinctive approach, as well as its unmatched resilience and integrated methods. We are dedicated to identifying the best market opportunities, and providing insightful information that will help your business thrive in the marketplace. Data Bridge offers tailored solutions to complex business challenges. This facilitates a smooth decision-making process. Data Bridge was founded in Pune in 2015. It is the product of deep wisdom and experience. Contact Us: Data Bridge Market Research US: +1 614 591 3140 UK: +44 845 154 9652 APAC: +653 1251 975 Email:- corporatesales@databridgemarketresearch.com This release was published on openPR.

People in Nunavut and northern Labrador have been writing to Canadian government officials this year to say grocers were charging exorbitant prices despite receiving a federal subsidy. The emails about the Nutrition North subsidy program ranged from desperate pleas to do something to lower food costs, to angry demands that retailers receiving subsidies be investigated. In April, Minister of Northern Affairs Dan Vandal acknowledged there was a problem. "I agree more work is needed to optimize the subsidy for Northerners to ensure 100 per cent of the subsidy is passed on directly to consumers," Vandal said in a note to Nunavut Family Services Minister Margaret Nakashuk obtained through an access to information request. Some of the 17 emails from members of the public accused retailers of hiking food prices in northern communities after funding arrived earlier this year through a program known as Jordan's Principle, which offers federal support to improve access for children to services and necessities including education and food. "Our food prices have increased since Jordan's Principle food for kids," said one message from October. "It's quite dismaying. Who profits on hunger?" The emails and notes were released in response to a request by The Canadian Press for correspondence with the Department of Northern Affairs about the Nutrition North Canada program, from the beginning of the year through Oct. 1. The federally run program offers subsidies to grocery companies operating in remote Indigenous communities aimed at offsetting the cost of transporting healthy foods, and making them more affordable. In one instance, a London, Ont., Girl Guide troop wrote asking the government to make Nutrition North more transparent. "We're worried that the money that is given does not help the cost of food in grocery stores go down enough," the letter said. The majority of the feedback was from people writing about prices in Nunavut and in Nain, which is the northernmost community in Labrador, in the Inuit region of Nunatsiavut. The main stores mentioned are those run by Arctic Co-operatives Ltd., which primarily serves Nunavut, and the North West Company, which operates 118 Northern stores in remote communities across Northern Canada. Names and identifying information about senders were redacted. "Put the subsidy up. The airlines are making millions and the North West Company, but the people are starving, please, please review these rates," a Nunavut resident wrote in February. "The stores in fact throw out foods that have rotted to the dump because they are priced too high and many people cannot afford them," said a July email about prices at Arctic Co-op and Northern stores. "Something else needs to be done to make the Nutrition North subsidy work like it was intended to, not make the people suffer and make the stores benefit." Another calls for an investigation into prices at the grocery stores in Nunavut. "One can of corn beef hash was $11 and now $14.09 after Jordan's (Principle) was introduced two months ago," the July email said. "Even a jar of sweet mixed pickles was over $32." As first reported by the Nunatsiaq News last week, Nunavut Tunngavik Inc., the land-claims body representing Nunavut Inuit, confirmed it is planning to investigate whether retailers hiked food prices after communities began receiving Jordan's Principle funding earlier this year. "NTI has heard concerns ... at our regular board meetings as well as the Nunavut roundtable on poverty reduction this past October," spokesperson Ivaluarjuk Merritt told The Canadian Press in an email Monday. Arctic Co-operatives Ltd. is owned by the 32 independent community co-op stores across the North, noted Duane Wilson, the company's vice-president of stakeholder relations. Since the company's shareholders are its customers, there is "absolutely zero incentive" to unfairly hike prices, he said in an interview Tuesday. Darryl Martin, a spokesperson for the North West Company said the company is working with communities in the North to deliver, via gift cards, the funding provided by Ottawa through Jordan's Principle -- also known as the Inuit Child First Initiative. He said the company shares the goal "of bringing more affordable food prices" to people in the North. In northern Labrador, one resident's February email urges Nutrition North advisory board members to "check in on Rigolet," a town where the North West Company operates the only grocery store. Several people from Nain sent emails to the department over the summer, when prices typically go down because retailers can ship food by ferry rather than pay for expensive air freight. "Why are grocery prices still outrageously high at Northern in Nain when we are in the middle of shipping season?" said one. A 10-pound bag of potatoes at Northern was selling for more than $31, the author said. A box of fish sticks was $21. The federal government announced last month it would launch an external, independent review of the Nutrition North subsidy program, with a final report expected in 2026. Lori Idlout, the New Democrat MP for Nunavut, said something needs to be done in the meantime to bring down "unbearable" food prices. "I think the Liberals don't care to help alleviate poverty among Indigenous communities and northern communities," Idlout said in a recent interview. "There needs to be a way to ensure that the Nutrition North program is holding accountable corporations like the (North West Company.)" The North West Company reported $219.8 million in gross profits for the second quarter of this year, a 7.8 per cent increase from the $204.4 million reported for the same time last year. A Toronto Metropolitan University published a study last year showing retailers passed on to consumers just 67 cents of every dollar received from the Nutrition North subsidy program. This report by The Canadian Press was first published Nov. 26, 2024. Shopping Trends The Shopping Trends team is independent of the journalists at CTV News. We may earn a commission when you use our links to shop. Read about us. 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BREAKING | Biden says Israel-Hezbollah ceasefire will take effect Wednesday morning A ceasefire between Israel and Lebanon's Hezbollah will take effect on Wednesday after both sides accepted an agreement brokered by the United States and France, U.S. President Joe Biden said on Tuesday. Loonie tanks after Trump threatens tariffs on Canadian goods The Canadian dollar fell to its lowest level since May 2020 after Donald Trump threatened to impose tariffs on Canadian goods shipped to the United States once he takes office in January. As Trump vows major tariff hike, a look at what the U.S. imports from Canada Some Canadian products could face huge tariffs on the first day of Donald Trump's administration in January. Here’s a quick look at what the U.S. imports from Canada. Canadian government suspends contracts with Boissonnault's former company The medical supply company co-founded by Liberal MP and former minister Randy Boissonnault has been suspended from bidding on or entering into contracts with the Government of Canada. Longtime member of Edmonton theatre community dies during 'A Christmas Carol' performance Edmonton's theatre community is in mourning after an actor died during a performance of "A Christmas Carol" at the Citadel Theatre on Sunday. Police chief says 'extreme left group' behind Montreal protest violence; Legault calls for more arrests Quebec Premier Francois Legault is putting pressure on the Montreal police to arrest everyone involved in an anti-NATO protest that turned violent last week. They thought they'd found Amelia Earhart's plane. Instead, the search continues The disappearance of pioneering aviator Amelia Earhart more than 87 years ago has remained one of the most captivating mysteries in history, with a handful of explorers devoted to scouring the seas for any clue to her final whereabouts. DEVELOPING | Trudeau confirms premiers meeting, Poilievre calls Trump tariff threat 'unjustified' Prime Minister Justin Trudeau will be convening a meeting of all of Canada's premiers 'this week' to discuss U.S. president-elect Donald Trump's intent to impose a 25 per cent tariff on all products from Canada and Mexico on his first day in office, if border issues aren't addressed. Vancouver B.C. teen with avian flu remains in critical care, source of infection still unknown The teenager who is infected with the first human case of H5N1 avian influenza acquired in Canada remains in critical care at BC Children’s Hospital, officials said Tuesday. B.C. RCMP officer won't stand trial for on-duty shooting A B.C. RCMP officer who was charged in an on-duty shooting nearly four years ago will not stand trial, prosecutors announced Tuesday. B.C. premier says Canada will negotiate from 'position of strength' on US tariff British Columbia Premier David Eby said Canada had to approach Donald Trump's plan to impose a 25 per cent U.S. tariff on Canadian goods from a position of strength, as business, trade and community organizations called for quick action on the trade threat. Toronto Ford says Trump's proposed 25 per cent tariff on Canadian goods like 'a family member stabbing you right in the heart' Ontario Premier Doug Ford says a 25 per cent tariff on all Canadian goods proposed by U.S. president-elect Donald Trump is akin to 'a family member stabbing you right in the heart.' BREAKING | Follow live: Serial killer Paul Bernardo denied parole for a third time Notorious killer Paul Bernardo has been denied parole for a third time following a hearing before the Parole Board of Canada. Traveller at Toronto Pearson airport caught with 45 kg of weed in her luggage: RCMP A 21-year-old woman has been charged after allegedly attempting to conceal 45 kilograms of cannabis in her luggage. Calgary TSB orders more training following incident involving plane in Calgary The Transportation Safety Board says an incident that involved a Westjet plane hitting the runway in Calgary earlier this year was connected to an issue with pilot training on a particular model of aircraft. Alberta Premier Danielle Smith says Trump's border concerns are valid as tariffs loom Alberta Premier Danielle Smith says Donald Trump’s concerns about the border are valid, as the president-elect threatens sweeping tariffs on Canadian goods. LIVE at 3:30 | Alberta to announce actions against Ottawa's proposed emissions cap The Alberta government is hitting back at the proposed federal emissions cap Tuesday afternoon. Ottawa 'It's insulting:' Ontario premier slams Trump on Canadian tariff threat Ontario Premier Doug Ford is reacting to a threat from incoming U.S. president-elect Donald Trump to impose tariffs on imports from Canada, calling the proposal ‘insulting’ and emphasizing the need for leaders to work together on a response. More winter weather expected this week in Ottawa A freezing rain warning in Ottawa has been lifted after a low-pressure system moved through eastern Ontario on Tuesday. Environment Canada says freezing rain will transition to rain as temperatures rise above 0 C this morning. Land near Dow's Lake being cleared in advance of new Civic Campus construction This is another step in the plan to construct a cutting-edge replacement for the aging Civic Campus, which just celebrated its 100th anniversary. Montreal Police chief says 'extreme left group' behind Montreal protest violence; Legault calls for more arrests Quebec Premier Francois Legault is putting pressure on the Montreal police to arrest everyone involved in an anti-NATO protest that turned violent last week. 'Broken lives and families,' former members of religious community speak out Several former members of fringe religious community the Mission de L’Esprit Saint are urging the Quebec government to intervene following claims that it was a cult that brainwashed some members. Their stories are being told in a new documentary by Noovo Info. BREAKING | Follow live: Serial killer Paul Bernardo denied parole for a third time Notorious killer Paul Bernardo has been denied parole for a third time following a hearing before the Parole Board of Canada. Edmonton Alberta Premier Danielle Smith says Trump's border concerns are valid as tariffs loom Alberta Premier Danielle Smith says Donald Trump’s concerns about the border are valid, as the president-elect threatens sweeping tariffs on Canadian goods. From Rogers Place to Winspear Centre, here's how accessible Edmonton concert venues are For most people buying a concert ticket, questions like “How am I going to get into a venue?” or “Where will I go to the bathroom?” aren’t top of mind, but for people with disabilities, these issues can make or break a night out. Stuff-a-Bus Week begins in Edmonton Edmonton Transit Service's stuff-a-bus campaign gets rolling Wednesday. Atlantic Nova Scotians head to the polls to vote in snap election; results delayed by an hour Nova Scotians are casting their votes Tuesday in a snap provincial election, but they won't learn the outcome until after 9 p.m., due to a delayed opening at a polling station. N.S. man charged with attempted murder after assault left victim with significant injuries A 30-year-old man is facing an attempted murder charge after an alleged assault in Denmark, N.S., on Monday. N.S. lobster buyer calls for heightened policing after shot fired into Meteghan home A lobster buyer in Meteghan, N.S., is looking for increased policing and a community-wide push aimed at organized crime after a bullet was fired into his home on Saturday night. Winnipeg 'It would mean a recession': Premier Kinew speaks on Trump's tariff threat Tariffs on Canadian goods headed to the United States would mean a recession in Manitoba. That is how Manitoba Premier Wab Kinew feels about comments from president-elect Donald Trump Monday. Steinbach man charged with child luring: RCMP A 20-year-old man from Steinbach has been charged with child luring, and RCMP have released one of his social media handles to help identify more victims. Advocates calling for action to help lower child poverty rates in Manitoba Recent data on child poverty in Canada showed Manitoba led the way with the highest child poverty rate, and now advocates are calling for action to lower the number. Regina Defence-called expert says Regina chiropractor accused of sexual assault followed industry standards An expert called by Ruben Manz’s defence counsel testified the Regina-based chiropractor, who is facing several sexual assault charges, followed the industry standard of care when treating the complainants. Alpacas and bison featured at second day of Agribition in Regina There is no shortage of livestock at the Canadian Western Agribition. While many people associate the event with cows and horses, Tuesday featured some less common animals: alpacas and bison. IN PICTURES | Here are the winners of the 2024 ExploreSask photo contest The winners of Tourism Saskatchewan's annual ExploreSask photo contest have been revealed. Kitchener 24 arrests as part of Hamilton, Ont. street gang investigation, with ties to Toronto, Waterloo and Brantford Police in Hamilton, Ont. have arrested 24 people as part of a street gang investigation with connections to Toronto, Halton, Waterloo and Brantford. Shelter in place lifted after police respond to barricaded person in Kitchener There is an increased police presence in a Kitchener neighbourhood as police respond to a call about a barricaded person. Victims' families urge parole board to keep 'sadistic' killer Bernardo behind bars The mothers of two teenage girls who were tortured and murdered by Paul Bernardo made emotional pleas at a Parole Board of Canada hearing Tuesday to keep the notorious killer and rapist behind bars, as he makes his third attempt to secure a release. Saskatoon Saskatoon man hospitalized after he was allegedly stabbed in the forehead A man has been taken to hospital after he was allegedly stabbed in the forehead early on Tuesday. City budget adjusted to include 5.84% property tax bump The City of Saskatoon's planned property tax increase in its proposed budget has been marginally bumped up to 5.84 per cent. Saskatoon businesses prepare for possible holiday impact amid Canada Post strike As Canada Post workers mark their second week on the picket line, some Saskatoon businesses say they’ve had to adapt to disruptions in postal services during their busiest time of year. Northern Ontario Committee OKs rezoning for former Sudbury hospital site Greater Sudbury's planning committee approved rezoning and official plan amendment for the former hospital in Sudbury at its meeting Monday. Suspect in attempted murder in Cobalt, Ont., makes court appearance The 18-year-old suspect charged in a disturbing attack on his ex-girlfriend was in court Tuesday morning. Sudbury resident scammed out of $20K, suspect from southern Ont. charged A 21-year-old from southern Ontario has been charged with several offences after a victim from Greater Sudbury was tricked into giving him $20,000. London Police look to identify 3 suspects in shooting investigation, arrest 4th suspect London police are asking the public for help identifying suspects involved in a break, enter and shooting investigation. Goderich woman’s 'passion' for Christmas on display for all to enjoy Ida Mcaulay loves Christmas. She loves it so much she has spent the past several weeks putting together a Christmas display that would make Santa Claus himself blush. Sending parents home with their healthy infants sooner, LHSC establishes permanent early discharge program The Early Discharge Program allows parents and newborns to be discharged, and have a midwife follow up with them at home to complete screening and assessments as opposed to having those take place in the hospital. Barrie One person seriously injured in collision with dump truck Emergency crews are at the scene of a serious collision between a dump truck and a minivan in Clearview Township. Multi-vehicle crash involving dump truck sends 3 to hospital Three people were hospitalized after police say a dump truck struck four vehicles in Newmarket on Monday afternoon. Midland murder trial enters final week with accused claiming self-defence The trial of a Midland man accused of murder in the fatal stabbing of his tenant three years ago is in its final week as the Crown and defence prepare to make their closing arguments to the jury. Windsor Two suspects wanted for pharmacy break-in Windsor police are searching for two suspects after a break-in at a pharmacy on Tecumseh Road East. Lakeshore man facing more sex assault charges after second alleged victim comes forward Essex County OPP say a Lakeshore man is facing more sexual assault charges after a second alleged victim has come forward. Amicable end proposed for former Grace Hospital site The Corporation of the City of Windsor and Fairmount Properties LLC issued a joint statement about the former Grace Hospital site near downtown Windsor. Vancouver Island B.C. premier says Canada will negotiate from 'position of strength' on US tariff British Columbia Premier David Eby said Canada had to approach Donald Trump's plan to impose a 25 per cent U.S. tariff on Canadian goods from a position of strength, as business, trade and community organizations called for quick action on the trade threat. B.C. teen with avian flu remains in critical care, source of infection still unknown The teenager who is infected with the first human case of H5N1 avian influenza acquired in Canada remains in critical care at BC Children’s Hospital, officials said Tuesday. B.C. RCMP officer won't stand trial for on-duty shooting A B.C. RCMP officer who was charged in an on-duty shooting nearly four years ago will not stand trial, prosecutors announced Tuesday. Kelowna Man in hospital following targeted shooting in Kamloops Police are appealing for information on a targeted shooting that resulted in the hospitalization of a man in Kamloops. Police cleared of fault in fatal 2023 crash in B.C.'s Interior British Columbia's independent police watchdog has cleared officers of wrongdoing in a crash where three people were killed south of Kamloops in July of last year. B.C. woman sentenced for stealing $14K in funds raised for schoolkids A B.C. woman who stole more than $14,000 in volunteer-raised funds that were supposed to be spent on school supplies and programs – including hot meals for vulnerable kids – won't spend any time in jail. Lethbridge 'Let's do this': Crowsnest Pass mayor wants proposed coal mine sooner than later A mayor in southwestern Alberta is hoping for an immediate meeting with Premier Danielle Smith to discuss a coal project his community has voted in favour of being built. Nenshi says not sending voter cards due to postal strike could affect byelection Alberta Opposition Leader Naheed Nenshi says a decision not to mail out voter registration cards due to the Canada Post strike could hurt turnout in a provincial byelection that's been called for a week before Christmas. Lethbridge business community concerned as Canada Post strike drags on Lethbridge businesses are starting to feel the pressure after 11 days of the Canada Post workers’ strike. The strike comes right as the Christmas shopping season is kicking into high gear. Sault Ste. Marie Sault police issue alert about surge in grandparent scams The Sault Ste. Marie Police Service warned residents Tuesday about a surge in grandparent scams targeting local senior citizens. Sault road reopens after building safely demolished A building on Queen Street East in Sault Ste. Marie is in danger of collapsing because of heavy snow. Hwy. 17 closed following fatal collision near Bruce Mines One person has been killed in a four-vehicle collision on Highway 17 east of Bruce Mines. N.L. 'Who profits on hunger?': Inuit send pleading emails to minister about food costs People in Nunavut and northern Labrador have been writing to Canadian government officials this year to say grocers were charging exorbitant prices despite receiving a federal subsidy. As N.L. firm pivots, scientists say Canada's green hydrogen dreams are far-fetched A Newfoundland energy company's embrace of data centres is raising doubts about eastern Canadian hopes of harnessing the region's howling winds to supply Germany with power from green hydrogen. Canadian leads group pushing Vatican for zero-tolerance policy on abuse by clergy An international group led by a Canadian is in Rome this week to push the Catholic Church to adopt a zero-tolerance policy on abuse by clergy. Local Spotlight Trailer Park Boys host Canadian premiere of new movie in Dartmouth Sunday night was a big night for the Trailer Park Boys, as Ricky, Julian and Bubbles hosted an advanced screening of their new movie in Dartmouth, N.S. Deer spotted wearing high-visibility safety jacket in Northern B.C. Andrea Arnold is used to having to slow down to let deer cross the road in her Northern B.C. community. But this weekend she saw something that made her pull over and snap a photo. From cellphones to dentures: Inside Halifax Transit’s lost and found Every single item misplaced on a bus or ferry in the Halifax Regional Municipality ends up in a small office at the Halifax Transit Bridge Terminal in Dartmouth, N.S. Torontonians identify priorities, concerns in new city survey A new public opinion survey has found that 40 per cent of Torontonians don’t feel safe, while half reported that the quality of life in the city has worsened over the last year. Longtime member of Edmonton theatre community dies during 'A Christmas Carol' performance Edmonton's theatre community is in mourning after an actor died during a performance of "A Christmas Carol" at the Citadel Theatre on Sunday. Beaver shot with arrow near Orillia on the road to recovery A beaver found with an arrow shot through its torso is now recovering at Shades of Hope Wildlife Refuge in Pefferlaw, Ont. after a massive rescue effort. 'I had no idea that they even existed': Family reunites with 80-year-old letters hidden in Winnipeg home The family of a soldier who fought during the Second World War has been reunited with letters written to him 80 years ago. The Thriftmas Special: The benefits of second-hand holiday shopping The holidays may be a time for family, joy and togetherness, but they can also be hard on the wallet. Video shows octopus 'hanging on for dear life' during bomb cyclone off B.C. coast Humans weren’t the only ones who struggled through the bomb cyclone that formed off the B.C. coast this week, bringing intense winds and choppy seas. Politics DEVELOPING | Trudeau confirms premiers meeting, Poilievre calls Trump tariff threat 'unjustified' Prime Minister Justin Trudeau will be convening a meeting of all of Canada's premiers 'this week' to discuss U.S. president-elect Donald Trump's intent to impose a 25 per cent tariff on all products from Canada and Mexico on his first day in office, if border issues aren't addressed. Canadian government suspends contracts with Boissonnault's former company The medical supply company co-founded by Liberal MP and former minister Randy Boissonnault has been suspended from bidding on or entering into contracts with the Government of Canada. Freeland says the two-month GST holiday is meant to tackle the 'vibecession' The federal government is hoping a temporary break on GST will address a 'vibecession' that has gripped Canadians, Finance Minister Chrystia Freeland said Monday. Health Doctors say it's fine to pee in the shower Here's a secret that’s not really a secret, many people pee in the shower. Maybe you're one of those people who don't care since it's all going down the same drain, or perhaps you're one of those who find it unhygienic. B.C. teen with avian flu remains in critical care, source of infection still unknown The teenager who is infected with the first human case of H5N1 avian influenza acquired in Canada remains in critical care at BC Children’s Hospital, officials said Tuesday. Quebec has highest rate in Canada of people under 25 diagnosed with ADHD According to the province’s Public Health Ministry, Quebec has the highest rate in the country of people under the age of 25 diagnosed with ADHD. Sci-Tech They thought they'd found Amelia Earhart's plane. Instead, the search continues The disappearance of pioneering aviator Amelia Earhart more than 87 years ago has remained one of the most captivating mysteries in history, with a handful of explorers devoted to scouring the seas for any clue to her final whereabouts. Majority of social media influencers don't verify information before sharing it, study finds A majority of social media influencers don't verify information before sharing it with their audiences, a study published Tuesday by the UN's scientific and cultural arm found, underscoring concerns that some of the biggest online figures can uncritically spread misleading claims. Ancient Egyptians drank a heady mix of alcohol, bodily fluids and hallucinogens during rituals, scientists say Researchers have discovered the residues of psychedelic drugs, bodily fluids and alcohol inside a 2,000-year-old mug, suggesting that ancient Egyptians imbibed hallucinogenic beverages during rituals. Entertainment 'No view' tickets for Taylor Swift's Vancouver shows reselling for thousands It appears that Swifties hoping to experience the final dates of the sold-out Eras Tour in December were given another chance Monday. It's almost time for Spotify Wrapped. When can you expect your 2024 recap? It's almost that time of year: Spotify is gearing up to release its annual Wrapped, personalized recaps of users' listening habits and year in audio. Economic impact of Taylor Swift's Eras Tour in Vancouver estimated at $157M Taylor Swift will bring an estimated $157-million economic impact to the city next week with the three final concert dates of the record-breaking Eras Tour, Destination Vancouver said. Business Bank of Canada says Trump's proposed tariffs would impact both economies The Bank of Canada said on Tuesday that if U.S. President-elect Donald Trump follows through on his threat of tariffs on Canada, it would have an impact on both economies and the central bank would incorporate those into its economic forecasts. Loonie tanks after Trump threatens tariffs on Canadian goods The Canadian dollar fell to its lowest level since May 2020 after Donald Trump threatened to impose tariffs on Canadian goods shipped to the United States once he takes office in January. Mexico suggests it would impose its own tariffs to retaliate against any Trump tariffs President Claudia Sheinbaum suggested Tuesday that Mexico could retaliate with tariffs of its own, after U.S. President-elect Donald Trump threatened to impose 25 per cent import duties on Mexican goods if the country doesn’t stop the flow of drugs and migrants across the border. Lifestyle World's oldest man dies aged 112 in England John Tinniswood, an Englishman born the same year the Titanic sank and who survived two world wars and two global pandemics, has died aged 112, Guinness World Records said on Tuesday, months after it recognized him as the world's oldest man. China's hottest new tourist attraction is 5,000 feet in the air The newest of these not-for-the-faint-of-heart structures is called Tianti (“Sky Ladder” in Chinese). It clocks in at 168 metres and stretches between two cliffs at a height of 5,000 feet, according to Chinese state media. Dictionary.com has named its word of the year, and it isn't 'brat' In an announcement Monday, Dictionary.com said one word experienced a 'meteoric rise in usage' in 2024. Sports NBA legend Charles Barkley criticizes LA Lakers over handling of Bronny James NBA legend Charles Barkley has criticized the Los Angeles Lakers over their handling of Bronny James this season. 'Embarrassing:' NHL team ditches bus and walks to Scotiabank Arena amid gridlock The Utah Hockey Club got the full Toronto experience Sunday night ahead of their first-ever matchup against the Maple Leafs—bumper-to-bumper traffic that forced the team to walk to the game. Vancouver Whitecaps drop head coach Vanni Sartini Two weeks after the Vancouver Whitecaps’ playoff run ended in the first round, the team has fired head coach Vanni Sartini. Autos Ontario woman buys van with odometer rolled back almost 100,000 kilometres An Ontario woman thought she got a good deal when she bought a van for $2,700, but later learned the odometer had been rolled back nearly 100,000 kilometres. Nearly 46,000 electric vehicles recalled in Canada over power loss risk Nearly 46,000 electric vehicles from Kia, Hyundai and Genesis are being recalled in Canada over a potential power loss issue that can increase the risk of a crash. Northvolt says Quebec battery plant will proceed despite bankruptcy filing Northvolt AB has filed for bankruptcy protection in the United States, but said the move will not jeopardize the manufacturer's planned electric vehicle battery plant in Quebec — though hundreds of millions of taxpayer dollars invested in the parent company could be lost. Stay Connected

AP Sports SummaryBrief at 4:19 p.m. ESTPhase 3 Study Results Demonstrated Three Year, Disease-Free Survival of 96% THOUSAND OAKS, Calif. , Dec. 7, 2024 /PRNewswire/ -- Amgen (NASDAQ: AMGN ) today announced new data demonstrating that adding BLINCYTO ® (blinatumomab) to chemotherapy significantly improves disease-free survival (DFS) in newly diagnosed pediatric patients with National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL) of average or higher risk of relapse. The data are from a Phase 3 study (AALL1731) conducted by the Children's Oncology Group. The results were simultaneously published in the New England Journal of Medicine and will be presented during the plenary session on Sunday, Dec. 8 , at 2 p.m. PT at the 66 th American Society of Hematology (ASH) Annual Meeting & Exposition in San Diego . "Over the last decade, BLINCYTO has reshaped the treatment landscape for B-ALL, offering a critical lifeline for thousands of adult and pediatric patients," said Jay Bradner , M.D., executive vice president of Research and Development and chief scientific officer at Amgen. "These powerful new data leave us little doubt about the profound impact of this medicine for a large number of children affected by this disease. We are grateful to the Children's Oncology Group, along with the patients, families and clinical teams, for their dedication and partnership in advancing this critical study to improve the lives of children with cancer." Based on the results of the first pre-specified interim analysis for efficacy, the study met its primary endpoint of DFS and study randomization was terminated early based on the recommendation from the data and safety monitoring committee due to the benefit observed in the BLINCYTO arm compared to the chemotherapy-only arm. Overall, the 3-year DFS was 96.0% for patients treated with chemotherapy plus BLINCYTO compared to 87.9% for those treated with only chemotherapy. The hazard ratio (HR) was 0.39 [95% confidence interval (CI) 0.24-0.64], indicating a 61% reduction in the risk of disease relapse, secondary malignant neoplasm or remission death with BLINCYTO. At 3 years, more patients remained alive and cancer free when treated with BLINCYTO plus chemotherapy compared to chemotherapy alone. "The AALL1731 study results are truly practice-changing, further solidifying blinatumomab's role as the standard of care for a large number of children with B-ALL," said Sumit Gupta , M.D., Ph.D., FRCPC, co-chair of the Children's Oncology Group AALL1731 study and oncologist and clinician investigator, Division of Haematology/Oncology at The Hospital for Sick Children (SickKids) and associate professor of pediatrics at the University of Toronto . "These breakthrough data showing a significant improvement in disease-free survival are poised to bring substantial clinical value to children with newly diagnosed B-ALL." The addition of BLINCYTO to chemotherapy in standard risk patients resulted in outcomes similar to those previously achieved in only the most favorable pediatric risk subsets. Among SR-Average patients, 3-year DFS was 97.5% for patients treated with BLINCYTO compared to 90.2% for those treated with only chemotherapy (HR 0.33, CI 0.15-0.69). For SR-High patients, 3-year DFS was 94.1% for those treated with BLINCYTO compared to 84.8% for those treated with only chemotherapy (HR 0.45, 95% CI 0.24-0.85). "Relapsed ALL remains a major cause of pediatric cancer mortality, with nearly half of the relapses occurring in children with standard-risk B-ALL," said Rachel E. Rau , M.D., co-chair of the Children's Oncology Group AALL1731 study, pediatric hematologist-oncologist at Seattle Children's Hospital and associate professor of pediatrics at the University of Washington . "These findings underscore the progress made with blinatumomab in preventing relapse and support its role as a critical addition to current therapeutic strategies." Safety results are consistent with the known safety profile of BLINCYTO. BLINCYTO has demonstrated a positive balance of benefits and risks, with only 0.3% of first courses associated with Grade 3+ cytokine release syndrome (CRS) and 0.7% with seizures. A higher risk of infections was observed in the BLINCYTO arm. These results provide the first evidence supporting BLINCYTO for use in the consolidation phase in newly diagnosed pediatric Philadelphia chromosome-negative (Ph-) B-ALL patients. This groundbreaking first-in-class Bispecific T-cell Engager (BiTE ® ) therapy is now backed by additional evidence reinforcing its role in redefining a standard of care for both adult and pediatric patients, starting from one month old, regardless of measurable residual disease (MRD) status. The findings further establish BLINCYTO as a versatile first-line consolidation therapy across all ages and treatment backbones. The NCI's Cancer Therapy Evaluation Program (CTEP), which sponsored the study will share data with the U.S. Food and Drug Administration as part of their ongoing communications relating to the trial. About The Children's Oncology Group The Children's Oncology Group (childrensoncologygroup.org), a member of the NCI National Clinical Trials Network (NCTN), is the world's largest organization devoted exclusively to childhood and adolescent cancer research. The Children's Oncology Group unites over 10,000 experts in childhood cancer at more than 200 leading children's hospitals, universities and cancer centers across North America , Australia , New Zealand and Saudi Arabia in the fight against childhood cancer. Today, more than 80% of the 15,000 children and adolescents diagnosed with cancer each year in the United States are cared for at Children's Oncology Group member institutions. Research performed by Children's Oncology Group institutions over the past 50 years has transformed childhood cancer from a virtually incurable disease to one with a combined 5-year survival rate of 86%. The Children's Oncology Group's mission is to improve the cure rate and outcomes for all children with cancer. About AALL1731 (NCT03914625) The AALL1731 study was a Phase 3 randomized trial to determine if two non-sequential cycles of BLINCYTO added to chemotherapy improved disease-free survival (DFS) in children with newly diagnosed pediatric National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL). The study enrolled 4,264 newly diagnosed NCI SR B-ALL patients, of whom 2,334 were risk stratified at the end of induction therapy as either SR-Average or SR-High. At the first planned interim efficacy analysis (data cutoff June 30, 2024 ), 1,440 of the eligible and evaluable patients had been randomized. The AALL1731 study was designed and conducted independently from industry. The Cancer Therapy Evaluation Program (CTEP) of the NCI sponsored the trial and provided funding to the Children's Oncology Group to conduct the study. NCI is part of the National Institutes of Health (NIH). In addition, Amgen provided BLINCYTO and support through an NCI Cooperative Research and Development Agreement. About Acute Lymphoblastic Leukemia (ALL) ALL, also known as acute lymphoblastic leukemia, is a fast-growing type of blood cancer that develops in the bone marrow and can sometimes spread to other parts of the body, including the lymph nodes, liver, spleen and central nervous system. ALL is a rare disease, with an estimated 6,550 new cases, affecting both children and adults, diagnosed in the U.S. in 2024. 1 B-ALL begins in immature cells that would normally develop into B-cell lymphocytes, which are white blood cells that grow in bone marrow. 2,3 B-ALL is the most common type of ALL, constituting approximately 75% of cases in adults and approximately 88% in children, the most common cancer in children. 4,5 About BLINCYTO ® (blinatumomab) BLINCYTO is the first globally approved Bispecific T-cell Engager (BiTE ® ) immuno-oncology therapy that targets CD19 surface antigens on B cells. BiTE ® molecules fight cancer by helping the body's immune system detect and target malignant cells by engaging T cells (a type of white blood cell capable of killing other cells perceived as threats) to cancer cells. By bringing T cells near cancer cells, the T cells can inject toxins and trigger cancer cell death (apoptosis). BiTE ® immuno-oncology therapies are currently being investigated for their potential to treat a wide variety of cancers. BLINCYTO was granted Breakthrough Therapy and Priority Review designations by the U.S. FDA and is approved in the U.S. for the treatment of: Adult and pediatric patients one month or older with CD19-positive Philadelphia chromosome-negative B-ALL during the consolidation phase of multiphase therapy. CD19-positive B-ALL in first or second complete remission with MRD greater than or equal to 0.1% in adults and pediatric patients one month or older. Relapsed or refractory CD19-positive B-ALL in adults and pediatric patients one month or older. In the European Union (EU), BLINCYTO is indicated as monotherapy for the treatment of: Adults with Philadelphia chromosome-negative CD19-positive relapsed or refractory B-ALL. Patients with Philadelphia chromosome-positive B-ALL should have failed treatment with at least two tyrosine kinase inhibitors (TKIs) and have no alternative treatment options. Adults with Philadelphia chromosome-negative CD19-positive B-ALL in first or second complete remission with MRD greater than or equal to 0.1%. Pediatric patients aged 1 year or older with Philadelphia chromosome-negative CD19-positive B-ALL which is refractory or in relapse after receiving at least two prior therapies or in relapse after receiving prior allogeneic hematopoietic stem cell transplantation. Pediatric patients aged 1 year or older with high-risk first relapsed Philadelphia chromosome-negative CD19-positive B-ALL as part of the consolidation therapy. BLINCYTO ® IMPORTANT SAFETY INFORMATION WARNING: CYTOKINE RELEASE SYNDROME and NEUROLOGICAL TOXICITIES including IMMUNE EFFECTOR CELL-ASSOCIATED NEUROTOXICITY SYNDROME Cytokine Release Syndrome (CRS), which may be life-threatening or fatal, occurred in patients receiving BLINCYTO ® . Interrupt or discontinue BLINCYTO ® and treat with corticosteroids as recommended. Neurological toxicities, including immune effector cell-associated neurotoxicity syndrome (ICANS) which may be severe, life-threatening, or fatal, occurred in patients receiving BLINCYTO ® . Interrupt or discontinue BLINCYTO ® as recommended. Contraindications BLINCYTO ® is contraindicated in patients with a known hypersensitivity to blinatumomab or to any component of the product formulation. Warnings and Precautions Cytokine Release Syndrome (CRS): CRS, which may be life-threatening or fatal, occurred in patients receiving BLINCYTO ® . The median time to onset of CRS is 2 days after the start of infusion and the median time to resolution of CRS was 5 days among cases that resolved. Closely monitor and advise patients to contact their healthcare professional for signs and symptoms of serious adverse events such as fever, headache, nausea, asthenia, hypotension, increased alanine aminotransferase (ALT), increased aspartate aminotransferase (AST), increased total bilirubin (TBILI), and disseminated intravascular coagulation (DIC). The manifestations of CRS after treatment with BLINCYTO ® overlap with those of infusion reactions, capillary leak syndrome (CLS), and hemophagocytic histiocytosis/macrophage activation syndrome (MAS). Using all of these terms to define CRS in clinical trials of BLINCYTO ® , CRS was reported in 15% of patients with R/R ALL, in 7% of patients with MRD-positive ALL, and in 16% of patients receiving BLINCYTO ® cycles in the consolidation phase of therapy. If severe CRS occurs, interrupt BLINCYTO ® until CRS resolves. Discontinue BLINCYTO ® permanently if life-threatening CRS occurs. Administer corticosteroids for severe or life-threatening CRS. Neurological Toxicities, including Immune Effector Cell-Associated Neurotoxicity Syndrome: BLINCYTO ® can cause serious or life-threatening neurologic toxicity, including ICANS. The incidence of neurologic toxicities in clinical trials was approximately 65%. The median time to the first event was within the first 2 weeks of BLINCYTO ® treatment. The most common (≥ 10%) manifestations of neurological toxicity were headache and tremor. Grade 3 or higher neurological toxicities occurred in approximately 13% of patients, including encephalopathy, convulsions, speech disorders, disturbances in consciousness, confusion and disorientation, and coordination and balance disorders. Manifestations of neurological toxicity included cranial nerve disorders. The majority of neurologic toxicities resolved following interruption of BLINCYTO ® , but some resulted in treatment discontinuation. The incidence of signs and symptoms consistent with ICANS in clinical trials was 7.5%. The onset of ICANS can be concurrent with CRS, following resolution of CRS, or in the absence of CRS. There is limited experience with BLINCYTO ® in patients with active ALL in the central nervous system (CNS) or a history of neurologic events. Patients with a history or presence of clinically relevant CNS pathology were excluded from clinical studies. Patients with Down Syndrome over the age of 10 years may have a higher risk of seizures with BLINCYTO ® therapy. Monitor patients for signs and symptoms of neurological toxicities, including ICANS, and interrupt or discontinue BLINCYTO ® as outlined in the PI. Advise outpatients to contact their healthcare professional if they develop signs or symptoms of neurological toxicities. Infections: Approximately 25% of patients receiving BLINCYTO ® in clinical trials experienced serious infections such as sepsis, pneumonia, bacteremia, opportunistic infections, and catheter-site infections, some of which were life-threatening or fatal. Administer prophylactic antibiotics and employ surveillance testing as appropriate during treatment. Monitor patients for signs or symptoms of infection and treat appropriately, including interruption or discontinuation of BLINCYTO ® as needed. Tumor Lysis Syndrome (TLS), which may be life-threatening or fatal, has been observed. Preventive measures, including pretreatment nontoxic cytoreduction and on-treatment hydration, should be used during BLINCYTO ® treatment. Monitor patients for signs and symptoms of TLS and interrupt or discontinue BLINCYTO ® as needed to manage these events. Neutropenia and Febrile Neutropenia, including life-threatening cases, have been observed. Monitor appropriate laboratory parameters (including, but not limited to, white blood cell count and absolute neutrophil count) during BLINCYTO ® infusion and interrupt BLINCYTO ® if prolonged neutropenia occurs. Effects on Ability to Drive and Use Machines: Due to the possibility of neurological events, including seizures and ICANS, patients receiving BLINCYTO ® are at risk for loss of consciousness, and should be advised against driving and engaging in hazardous occupations or activities such as operating heavy or potentially dangerous machinery while BLINCYTO ® is being administered. Elevated Liver Enzymes: Transient elevations in liver enzymes have been associated with BLINCYTO ® treatment with a median time to onset of 3 days. In patients receiving BLINCYTO ® , although the majority of these events were observed in the setting of CRS, some cases of elevated liver enzymes were observed outside the setting of CRS, with a median time to onset of 19 days. Grade 3 or greater elevations in liver enzymes occurred in approximately 7% of patients outside the setting of CRS and resulted in treatment discontinuation in less than 1% of patients. Monitor ALT, AST, gamma-glutamyl transferase, and total blood bilirubin prior to the start of and during BLINCYTO ® treatment. BLINCYTO ® treatment should be interrupted if transaminases rise to > 5 times the upper limit of normal (ULN) or if total bilirubin rises to > 3 times ULN. Pancreatitis: Fatal pancreatitis has been reported in patients receiving BLINCYTO ® in combination with dexamethasone in clinical trials and the post-marketing setting. Evaluate patients who develop signs and symptoms of pancreatitis and interrupt or discontinue BLINCYTO ® and dexamethasone as needed. Leukoencephalopathy: Although the clinical significance is unknown, cranial magnetic resonance imaging (MRI) changes showing leukoencephalopathy have been observed in patients receiving BLINCYTO ® , especially in patients previously treated with cranial irradiation and antileukemic chemotherapy. Preparation and administration errors have occurred with BLINCYTO ® treatment. Follow instructions for preparation (including admixing) and administration in the PI strictly to minimize medication errors (including underdose and overdose). Immunization: Vaccination with live virus vaccines is not recommended for at least 2 weeks prior to the start of BLINCYTO ® treatment, during treatment, and until immune recovery following last cycle of BLINCYTO ® . Benzyl Alcohol Toxicity in Neonates: Serious adverse reactions, including fatal reactions and the "gasping syndrome," have been reported in very low birth weight (VLBW) neonates born weighing less than 1500 g, and early preterm neonates (infants born less than 34 weeks gestational age) who received intravenous drugs containing benzyl alcohol as a preservative. Early preterm VLBW neonates may be more likely to develop these reactions, because they may be less able to metabolize benzyl alcohol. Use the preservative-free preparations of BLINCYTO ® where possible in neonates. When prescribing BLINCYTO ® (with preservative) for neonatal patients, consider the combined daily metabolic load of benzyl alcohol from all sources including BLINCYTO ® (with preservative), other products containing benzyl alcohol or other excipients (e.g., ethanol, propylene glycol) which compete with benzyl alcohol for the same metabolic pathway. Monitor neonatal patients receiving BLINCYTO ® (with preservative) for new or worsening metabolic acidosis. The minimum amount of benzyl alcohol at which serious adverse reactions may occur in neonates is not known. The BLINCYTO ® 7-Day bag (with preservative) contains 7.4 mg of benzyl alcohol per mL. Embryo-Fetal Toxicity: Based on its mechanism of action, BLINCYTO ® may cause fetal harm when administered to a pregnant woman. Advise pregnant women of the potential risk to the fetus. Advise females of reproductive potential to use effective contraception during treatment with BLINCYTO ® and for 48 hours after the last dose. Adverse Reactions The safety of BLINCYTO ® in adult and pediatric patients one month and older with MRD-positive B-cell precursor ALL (n=137), relapsed or refractory B-cell precursor ALL (n=267), and Philadelphia chromosome-negative B-cell precursor ALL in consolidation (n=165) was evaluated in clinical studies. The most common adverse reactions (≥ 20%) to BLINCYTO ® in this pooled population were pyrexia, infusion-related reactions, headache, infection, musculoskeletal pain, neutropenia, nausea, anemia, thrombocytopenia, and diarrhea. Dosage and Administration Guidelines BLINCYTO ® is administered as a continuous intravenous infusion at a constant flow rate using an infusion pump which should be programmable, lockable, non-elastomeric, and have an alarm. It is very important that the instructions for preparation (including admixing) and administration provided in the full Prescribing Information are strictly followed to minimize medication errors (including underdose and overdose). INDICATIONS BLINCYTO ® (blinatumomab) is indicated for the treatment of CD19-positive B-cell precursor acute lymphoblastic leukemia (ALL) in adult and pediatric patients one month and older with: Philadelphia chromosome-negative disease in the consolidation phase of multiphase chemotherapy. Minimal residual disease (MRD) greater than or equal to 0.1% in first or second complete remission. Relapsed or refractory disease. Please see BLINCYTO ® full Prescribing Information , including BOXED WARNINGS. About Bispecific T-Cell Engager (BiTE ® ) Technology BiTE technology is a targeted immuno-oncology platform that is designed to engage a patient's own T cells to any tumor-specific antigen, activating the cytotoxic potential of T cells to eliminate detectable cancer. The BiTE immuno-oncology platform has the potential to treat different cancer types through tumor-specific antigens. The BiTE platform has a goal of leading to off-the-shelf solutions, which have the potential to make innovative T-cell treatment available to all providers when their patients need it. For more than a decade, Amgen has been advancing this innovative technology, which has demonstrated strong efficacy in hematological malignancies and now a solid tumor with the approval of IMDELLTRA. Amgen remains committed to progressing multiple BiTE molecules across a broad range of hematologic and solid tumor malignancies, paving the way for additional applications in more tumor types. Amgen is further investigating BiTE technology with the goal of enhancing patient experience and therapeutic potential. To learn more about BiTE technology, visit BiTE ® Technology 101 . About Amgen Amgen discovers, develops, manufactures and delivers innovative medicines to help millions of patients in their fight against some of the world's toughest diseases. More than 40 years ago, Amgen helped to establish the biotechnology industry and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what's known today. Amgen is advancing a broad and deep pipeline that builds on its existing portfolio of medicines to treat cancer, heart disease, osteoporosis, inflammatory diseases and rare diseases. 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Amgen may not be able to access the capital and credit markets on terms that are favorable to it, or at all. Any scientific information discussed in this news release relating to new indications for Amgen's products is preliminary and investigative and is not part of the labeling approved by the U.S. Food and Drug Administration for the products. The products are not approved for the investigational use(s) discussed in this news release, and no conclusions can or should be drawn regarding the safety or effectiveness of the products for these uses. CONTACT: Amgen, Thousand Oaks Elissa Snook , 609-251-1407 (media) Justin Claeys , 805-313-9775 (investors) References SOURCE Amgen