Breakthrough in scalable production of high-quality organoids November 25, 2024 Pohang University of Science & Technology (POSTECH) Introducing the innovative 'UniMat' platform utilizing 3D engineered nanofiber membrane. Facebook Twitter Pinterest LinkedIN Email A research team led by Professor Dong Sung Kim and researcher Dohui Kim from the Department of Mechanical Engineering at POSTECH (Pohang University of Science and Technology) has successfully developed a platform capable of scalable, uniform production of organoids that mimic biological functions. The project was carried out in collaboration with Professor Tae-Eun Park and researcher Hyeonji Lim from the Department of Biomedical Engineering at UNIST (Ulsan National Institute of Science and Technology). This groundbreaking research has recently been published in the online edition of Nature Communications . Organoids are three-dimensional cellular constructs that replicate the functions of human organs, attracting significant attention in the fields of human organ development, disease modeling, and regenerative medicine research. However, the heterogeneity and low reproducibility of organoids present challenges for their scalable production, limiting their practical application in clinical trials and drug development processes. Additionally, current technologies face limitations in producing organoids at scale, falling short of meeting industrial demands. To address these challenges, the research team has developed a platform called UniMat (Uniform and Mature Organoid Culture Platform), which enables the scalable production of mature organoids. This platform is implemented using a three-dimensional engineered membrane made of extremely fine nanofibers -- about 1/200 the width of a human hair -- providing a structural environment that allows for uniform organoid formation while also enhancing nutrient and differentiation factor delivery through material permeability, which is crucial for organoid differentiation and maturation. Using UniMat, the team successfully produced kidney organoids featuring nephron structures and blood vessels similar to those found in human kidneys from human-induced pluripotent stem cells, achieving consistent quality and greatly improving production efficiency. Furthermore, they used UniMat to establish a polycystic kidney disease model, demonstrating the potential for standardized organoid-based disease modeling and drug evaluation. Professor Dong Sung Kim of POSTECH, who led the research, explained the significance of the study: "Through these research outcomes, we not only accelerate organoid-based R&D that requires high reproducibility and reliability, but we also expect to make significant contributions to the development of animal alternative testing methods, which are gaining increasing attention. By addressing both the quality assurance and scalable production challenges of organoids with UniMat, we have laid the foundation for the practical application of organoids in clinical and pharmaceutical industries." This research was supported by the Bio & Medical Technology Development Program, Mid-Career Researcher Program, and Young Researcher Program funded by the National Research Foundation of Korea and the Ministry of Science and ICT, as well as the Alchemist Project funded by the Ministry of Trade, Industry and Energy. Story Source: Materials provided by Pohang University of Science & Technology (POSTECH) . Note: Content may be edited for style and length. Journal Reference : Cite This Page :A Look Into Eaton Corp Inc's Price Over EarningsArticle content Matthew Waples is pumped up about the possibility of launching his own graphic design business. The craft has been his stock and trade for more than 20 years; he’s worked for others, is currently freelancing and is now determined to put more of his personal stamp on product. “I know the T-shirt industry ... it’s kind of my niche,” says the Sault Ste. Marie man. A business-owner buddy has agreed to back the project. Everything appears geared to go. There’s just one wrench. Waples, 43, was diagnosed earlier this year with t esticular cancer and is being further tested for what could be adrenal-gland cancer. It is, indeed, a major setback, but Waples says he’s determined to see the ordeal through and come out the other side happy and successful, working for himself doing what he loves. “Now I’ve got to stay alive,” Waples told The Sault Star in an interview. “That’s a carrot that makes me ... I have a goal and a dream. So, once I get through this, I have something to do. It’s keeping me wanting to stay here.” Waples said he’s been told the testicular cancer appears to have been initially caused by a mass on his adrenal gland above the kidney. Currently, surgery to remove the affected testicle is slated for December, followed by chemotherapy. But things may happen sooner given grim news Waples recently received. On Nov. 18, Waples went to hospital with “severe” testicle pain and was told the tumour had doubled in size in only two months. Surgery may very well be bumped up if pain does not subside. Waples remembers well – and exactly what he was doing – the day things really began to go south. It was June 24, the day the Florida Panthers captured their first Stanley Cup in franchise history with a 2-1 Game 7 victory over the Edmonton Oilers. Waples, who drums, was moving instruments with a friend when he began experiencing severe pain. “I was like, ‘What the f#@k is going on here?’” he recalled thinking. He initially thought it was hernia; d rumming and playing goalie in hockey when he was younger have yielded back problems for years. “I don’t like to go to the hospital unless I have to,” Waples said. But a nurse friend insisted he go to the emergency department just to be sure. Testing ultimately revealed the cancer. Naturally, Waples was shocked and scared. But there were warning signs. Over the past year, he suffered “significant” weight loss and took it upon himself to at least start eating better. “When I was younger, I ate garbage, and I didn’t take care of myself, and I put the wrong things in my body,” he said. “And I think that, in part, that’s why things are happening now.” His past has prompted him to be public about his illness. “There’s nothing wrong with making mistakes, but you’ve got to turn things around if you want to survive,” Waples said. Candour also serves another purpose. The testicle removal will likely take place in the Sault, but further procedures and treatment will likely have to be carried out in southern Ontario, likely Toronto. Waples, who is on ODSP and doesn’t currently have a vehicle, fears flights to Toronto will be beyond his means. Northern Health Travel Grant benefits alone wouldn’t likely cut it, either, as travel costs are shouldered up front. “And I have zero means of getting it before the fact,” Waples said. Currently single, he also wants to have sperm frozen should he decide, later on, to start a family. “I don’t know what the future holds ... I’ve always wanted a family,” Waples said. “If the drive that I have to accomplish everything after this life-changing thing, if that is to come to fruition and I meet a girl who is 10 years younger than me and wants a family, and I can even give the possibility of that.” A GoFundMe page ( https://www.gofundme.com/f/MattWaplesCancer ) has been set up. As of Monday morning, $2,008 was raised toward an $8,108 goal. “I’m not looking for sympathy,” Waples said. “Every single one of us is going to face something in our lives I’m no more special or different than anybody else. But I’ve got two or three weeks to make things happen or they’re not going to happen.” jougler@postmedia.com On X: @JeffreyOugler Share this Story : ‘I’ve got to stay alive’: Matthew Waples determined to beat testicular cancer, start own business Copy Link Email X Reddit Pinterest LinkedIn Tumblr
College Football Playoff's first 12-team bracket is set with Oregon No. 1 and SMU in, Alabama out SMU captured the last open spot in the 12-team College Football Playoff, bumping Alabama to land in a bracket that placed undefeated Oregon at No. 1. The selection committee preferred the Mustangs, losers of a heartbreaker in the Atlantic Coast Conference title game, who had a far less difficult schedule than Alabama of the SEC but one fewer loss. The inaugural 12-team bracket marks a new era for college football, though the Alabama-SMU debate made clear there is no perfect formula. The tournament starts Dec. 20-21 with four first-round games. It concludes Jan. 20 with the national title game in Atlanta. Alabama left out of playoff as committee rewards SMU's wins over Crimson Tide's strong schedule The College Football Playoff committee took wins over strength of schedule, taking SMU over Alabama for the final at-large spot in the field. The field was expanded from four to 12 teams this season, but that didn’t save the committee from controversy. SMU showed it could compete against a traditional power, losing to Clemson 34-31 on a 56-yard field goal in the ACC title game on Saturday. Alabama had some ups and downs in its first season under coach Kalen DeBoer. The Crimson Tide had quality wins against Georgia and South Carolina, but lost at Vanderbilt, Tennessee and Oklahoma. Big Ten wins playoff selection derby, followed by SEC despite notable Alabama omission College football’s conference shakeup left concerns about two super conferences dominating the playoff field. They weren’t totally unfounded, or 100% born out. The Big Ten, not the Southeastern Conference, was the biggest winner. The ACC scored, too. The Big Ten led the initial 12-team playoff field with four making the cut, topped by a No. 1 Oregon team that was part of the Pac-12 exodus. Then came the SEC — and one notable omission. ACC runner-up SMU got the nod over college football blue-blood Alabama, another blemish in Kalen DeBoer’s first season as Nick Saban’s championship-or-bust successor. Darnold delivers for Vikings with career-high 347 yards and 5 TDs to beat Falcons, Cousins 42-21 MINNEAPOLIS (AP) — Sam Darnold threw for 347 yards and five touchdowns, both career highs, and the Minnesota Vikings pulled away from Kirk Cousins and the Atlanta Falcons 42-21 for their sixth straight victory. Darnold added another highlight to his brilliant first season with the Vikings following Cousins' departure in free agency to Atlanta with a 22-for-28 performance and no turnover-worthy plays despite heavy first-half pressure. Jordan Addison had eight catches for 133 yards and three scores and Justin Jefferson racked up seven receptions for 132 yards and two touchdowns. Cousins threw two more interceptions without a touchdown in his return to Minnesota. Saquon Barkley sets Eagles season rushing record and has Dickerson's NFL mark in his sights PHILADELPHIA (AP) — Saquon Barkley has broken LeSean McCoy's Eagles franchise record for rushing yards in a season. Barkley has 1,623 yards. He surpassed McCoy's mark of 1,607 yards with a 9-yard run in Sunday's 22-16 win over Carolina. Barkley finished the game with 124 yards, within a yard of his season average. He has four games left and is on pace to break Eric Dickerson's 40-year-old NFL record of 2,105 yards. Dickerson set that record in a 16-game season and Barkley has one more game. Eagles fans serenaded Barkley with “MVP!” chants and McCoy congratulated him on social media. Saints QB Derek Carr injures left hand on dive in 4th quarter of win over Giants EAST RUTHERFORD, N.J. (AP) — New Orleans Saints quarterback Derek Carr injured his left hand late in the fourth quarter of Sunday’s 14-11 victory over the New York Giants when he went airborne while trying for a first down and crashed to the turf. Carr tried to leap over a Giants tackler and landed at the New Orleans 39-yard line, extending his non-throwing hand to break his fall. He was on the turf for a minute or two before walking to the medical tent. He was examined and slowly walked to an area where X-rays are done. The injury could hurt the already slim playoff hopes of the Saints. Tamar Bates scores 29 points to help Missouri beat No. 1 Kansas 76-67 COLUMBIA, Mo. (AP) — Tamar Bates had 29 points and five steals to help Missouri beat Hunter Dickinson and No. 1 Kansas 76-67. Mark Mitchell scored 17 points in Missouri’s first win over Kansas since a 74-71 victory on Feb. 4, 2012. Anthony Robinson II had 11 points and five steals for the 8-1 Tigers. Dickinson had 19 points and 14 rebounds, but he also committed seven turnovers. The 7-2 Jayhawks have lost two straight on the road after falling 76-63 against Creighton on Wednesday night. Scottie Scheffler ends his big year in the Bahamas with his 9th victory NASSAU, Bahamas (AP) — Scottie Scheffler ended his biggest year with another victory. Scheffler was coming off a two-month break and looked as good as ever. He shot 63 in the Hero World Challenge and set tournament records at Albany with a 72-hole total of 263 and a six-shot victory. Tom Kim was the runner-up and Justin Thomas finished third. Scheffler ends his year with nine victories in 21 tournaments. That includes the holiday tournament in the Bahamas and the Olympic gold medal in Paris. It's the third-highest winning percentage in the last 40 years. Tournament host Tiger Woods had two better years. Lindsey Vonn is encouraged by how close she is to being competitive in ski racing return at age 40 COPPER MOUNTAIN, Colo. (AP) — Lindsey Vonn is encouraged by how close she is to being competitive again in her ski racing return at 40 years old. Vonn is still getting her ski equipment dialed in and getting used to going full speed again on her new titanium knee. That’s why all that she's reading into being more than two seconds behind in a pair of lower-level super-G races Sunday is that she’s right there. This after nearly six years away from ski racing and an abbreviated prep period. She was 2.19 seconds behind in the first race and 2.06 in the second. Both were won by her American teammate Lauren Macuga. Plane circles MetLife Stadium with message to co-owner John Mara to fix the Giants' 'dumpster fire' EAST RUTHERFORD, N.J. (AP) — A small plane circled MetLife Stadium roughly 90 minutes before New York was to play host to the New Orleans Saints on Sunday, asking Giants co-owner John Mara to overhaul the team that has made the playoffs twice since winning the Super Bowl in February 2012. “Mr. Mara, enough. Please fix this dumpster fire!” the message read as it was towed behind the rear of a small plane.None
— Oct. 1, 1924: James Earl Carter Jr. is born in Plains, Georgia, son of James Sr. and Lillian Gordy Carter. — June 1946: Carter graduates from the U.S. Naval Academy. — July 1946: Carter marries Rosalynn Smith, in Plains. They have four children, John William (“Jack”), born 1947; James Earl 3rd (“Chip”), 1950; Donnel Jeffrey (Jeff), 1952; and Amy Lynn, 1967. — 1946-1953: Carter serves in a Navy nuclear submarine program, attaining rank of lieutenant commander. — Summer 1953: Carter resigns from the Navy, returns to Plains after father’s death. — 1953-1971: Carter helps run the family peanut farm and warehouse business. — 1963-1966: Carter serves in the Georgia state Senate. — 1966: Carter tries unsuccessfully for the Democratic gubernatorial nomination. — November 1970: Carter is elected governor of Georgia. Serves 1971-75. — Dec. 12, 1974: Carter announces a presidential bid. Atlanta newspaper answers with headline: “Jimmy Who?” — January 1976: Carter leads the Democratic field in Iowa, a huge campaign boost that also helps to establish Iowa’s first-in-the-nation caucus. — July 1976: Carter accepts the Democratic nomination and announces Sen. Walter Mondale of Minnesota as running mate. — November 1976: Carter defeats President Gerald R. Ford, winning 51% of the vote and 297 electoral votes to Ford’s 240. — January 1977: Carter is sworn in as the 39th president of the United States. On his first full day in office, he pardons most Vietnam-era draft evaders. —September 1977: U.S. and Panama sign treaties to return the Panama Canal back to Panama in 1999. Senate narrowly ratifies them in 1978. — September 1978: Egyptian President Anwar Sadat, Israeli Prime Minister Menachem Begin and Carter sign Camp David accords, which lead to a peace deal between Egypt and Israel the following year. — June 15-18, 1979: Carter attends a summit with Soviet President Leonid Brezhnev in Vienna that leads to the signing of the SALT II treaty. — November 1979: Iranian militants storm the U.S. Embassy in Tehran, taking 52 hostages. All survive and are freed minutes after Carter leaves office in January 1981. — April 1980: The Mariel boatlift begins, sending tens of thousands of Cubans to the U.S. Many are criminals and psychiatric patients set free by Cuban leader Fidel Castro, creating a major foreign policy crisis. — April 1980: An attempt by the U.S. to free hostages fails when a helicopter crashes into a transport plane in Iran, killing eight servicemen. — Nov. 4, 1980: Carter is denied a second term by Ronald Reagan, who wins 51.6% of the popular vote to 41.7% for Carter and 6.7% to independent John Anderson. — 1982: Jimmy and Rosalynn Carter co-found The Carter Center in Atlanta, whose mission is to resolve conflicts, protect human rights and prevent disease around the world. — September 1984: The Carters spend a week building Habitat for Humanity houses, launching what becomes the annual Carter Work Project. — October 1986: A dedication is held for The Carter Presidential Center in Atlanta. The center includes the Carter Presidential Library and Museum and Carter Center offices. — 1989: Carter leads the Carter Center’s first election monitoring mission, declaring Panamanian Gen. Manuel Noriega’s election fraudulent. — May 1992: Carter meets with Mikhail and Raisa Gorbachev at the Carter Center to discuss forming the Gorbachev Foundation. — June 1994: Carter plays a key role in North Korea nuclear disarmament talks. — September 1994: Carter leads a delegation to Haiti, arranging terms to avoid a U.S. invasion and return President Jean-Bertrand Aristide to power. — December 1994: Carter negotiates tentative cease-fire in Bosnia. — March 1995: Carter mediates cease-fire in Sudan’s war with southern rebels. — September 1995: Carter travels to Africa to advance the peace process in more troubled areas. — December 1998: Carter receives U.N. Human Rights Prize on 50th anniversary of the Universal Declaration of Human Rights. — August 1999: President Bill Clinton awards Jimmy and Rosalynn Carter the Presidential Medal of Freedom. — September 2001: Carter joins former Presidents Ford, Bush and Clinton at a prayer service at the National Cathedral in Washington after Sept. 11 attacks. — April 2002: Carter’s book “An Hour Before Daylight: Memories of a Rural Boyhood” chosen as finalist for Pulitzer Prize in biography. — May 2002: Carter visits Cuba and addresses the communist nation on television. He is the highest-ranking American to visit in decades. — Dec. 10, 2002: Carter is awarded the Nobel Peace Prize for his “untiring effort to find peaceful solutions to international conflicts, to advance democracy and human rights, and to promote economic and social development.” — July 2007: Carter joins The Elders, a group of international leaders brought together by Nelson Mandela to focus on global issues. — Spring 2008: Carter remains officially neutral as Sens. Barack Obama and Hillary Rodham Clinton battle each other for the Democratic presidential nomination. — April 2008: Carter stirs controversy by meeting with the Islamic militant group Hamas. — August 2010: Carter travels to North Korea as the Carter Center negotiates the release of an imprisoned American teacher. — August 2013: Carter joins President Barack Obama and former President Bill Clinton at the 50th anniversary of the Rev. Martin Luther King Jr.’s “I Have A Dream” speech and the March on Washington. — Oct. 1, 2014: Carter celebrates his 90th birthday. — December 2014: Carter is nominated for a Grammy in the best spoken word album category, for his book “A Call To Action.” — May 2015: Carter returns early from an election observation visit in Guyana — the Carter Center’s 100th — after feeling unwell. — August 2015: Carter has a small cancerous mass removed from his liver. He plans to receive treatment at Emory Healthcare in Atlanta. — August 2015: Carter announces that his grandson Jason Carter will chair the Carter Center governing board. — March 6, 2016: Carter says an experimental drug has eliminated any sign of his cancer, and that he needs no further treatment. — May 25, 2016: Carter steps back from a “front-line” role with The Elders to become an emeritus member. — July 2016: Carter is treated for dehydration during a Habitat for Humanity build in Canada. — Spring 2018: Carter publishes “Faith: A Journey for All,” the last of 32 books. — March 22, 2019: Carter becomes the longest-lived U.S. president, surpassing President George H.W. Bush, who died in 2018. — September 18, 2019: Jimmy and Rosalynn Carter deliver their final in-person annual report at the Carter Center. — October 2019: At 95, still recovering from a fall, Carter joins the Work Project with Habitat for Humanity in Nashville, Tennessee. It’s the last time he works personally on the annual project. — Fall 2019-early 2020: Democratic presidential hopefuls visit, publicly embracing Carter as a party elder, a first for his post-presidency. — November 2020:The Carter Center monitors an audit of presidential election results in the state of Georgia, marking a new era of democracy advocacy within the U.S. — Jan. 20, 2021: The Carters miss President Joe Biden’s swearing-in, the first presidential inauguration they don’t attend since Carter’s own ceremony in 1977. The Bidens later visit the Carters in Plains on April 29. — Feb. 19, 2023: Carter enters home hospice care after a series of short hospital stays. — July 7, 2023: The Carters celebrate their 77th and final wedding anniversary. — Nov. 19, 2023: Rosalynn Carter dies at home, two days after the family announced that she had joined the former president in receiving hospice care. — Oct. 1, 2024 — Carter becomes the first former U.S. president to reach 100 years of age , celebrating at home with extended family and close friends. — Oct. 16, 2024 — Carter casts a Georgia mail ballot for Democratic presidential nominee Kamala Harris, having told his family he wanted to live long enough to vote for her. It marks his 21st presidential election as a voter. — Dec. 29, 2024: Carter dies at home.
CANEX Closes Final Tranche of Equity FinancingHome | New PM Bayrou faces ‘long road’ against fractious French parliament French President Emmanuel Macron named key ally Francois Bayrou as his fourth prime minister of 2024 on Friday, but the scale of the challenge facing the veteran centrist was immediately clear as the Socialist Party refused to join his coalition government. Bayrou, 73, gave a sober assessment of whether he could tame a hung parliament that ousted his predecessor, Michel Barnier, just last week. “It is a long road, everyone knows that,” he told reporters. “I am not the first to take a long road.” France’s festering political malaise has raised doubts about whether Macron will complete his second presidential term until 2027. It has also lifted French borrowing costs and left a power vacuum in the heart of Europe, just as Donald Trump heads to the White House and Germany braces for new elections following the collapse of its governing coalition. Bayrou, the founder of the Democratic Movement (MoDem) party which has been a part of Macron’s ruling alliance since 2017, has himself run for president three times, leaning on his rural roots as the longtime mayor of the southwestern town of Pau. His immediate priority will be passing a special law to roll over the 2024 budget, with a nastier battle over the belt-tightening 2025 legislation looming early next year. Parliamentary pushback over the 2025 bill led to Barnier’s downfall and left-wing leaders on Friday announced they might try to topple Bayrou as well should he use special constitutional powers to ram through the budget against parliament. Bayrou’s proximity to the deeply unpopular Macron may also prove to be a vulnerability. The Socialist Party, which Macron courted during his prime ministerial search, accused the president of ignoring their demands for a leftist leader in favour of a “risky” Macronista. “We will thus not enter the government and remain in the opposition,” said Boris Vallaud, the leader of the Socialists’ parliamentary bloc. VIEW FROM THE LEFT Reaction to Bayrou’s appointment on the left will be a concern for Macron, with the prime minister likely living day-to-day, at the mercy of the president’s opponents, for the foreseeable future. Macron will hope Bayrou can stave off no-confidence votes until at least July, when France will be able to hold a new parliamentary election. Far-left France Unbowed party leaders said they would be seeking to immediately remove Bayrou, while leaders from other left-wing parties took a more nuanced approach. Greens boss Marine Tondelier also said she would support a no-confidence motion if the prime minister ignored their tax and pensions concerns. Communist leader Fabien Roussel said his party would hold fire against Bayrou and decide on a case-by-case basis if he promises not to ram through legislation. Jordan Bardella, president of the far-right National Rally (RN) party, said it would not be calling for an immediate no-confidence motion, while fellow RN leader Marine Le Pen said Bayrou should listen to the opposition’s budgetary wishes. REAL TEST OVER 2025 BUDGET LOOMS Barnier’s budget bill, which aimed for 60 billion euros ($63 billion) in savings to assuage investors increasingly concerned by France’s 6% deficit, was deemed too miserly by the far-right and left. The government’s failure to find a way out of the gridlock has seen French borrowing costs push higher. XTB Research Director Kathleen Brooks said Bayrou’s appointment was unlikely to have a major impact on French bonds. However, she said the CAC 40 French stock index is underperforming German stocks by a three-decade margin. “With France still mired in political turmoil, narrowing this gap is an uphill struggle, even with a new PM,” she wrote. Macron named Bayrou as justice minister in 2017 but he resigned only weeks later amid an investigation into his party’s alleged fraudulent employment of parliamentary assistants. He was acquitted of fraud charges this year. SABC © 2024
Washington Capitals star Alex Ovechkin has a broken left fibula and is expected to miss 4 to 6 weeksCondolences poured in from around the globe Sunday as word spread of the death of former President Jimmy Carter in his hometown in Georgia at the age of 100 — with all the remaining living US presidents offering personal tributes. “Whenever I had a chance to spend time with President Carter, it was clear that he didn’t just profess these values,” former President Barack Obama said in a statement . “He embodied them. And in doing so, he taught all of us what it means to live a life of grace, dignity, justice, and service. “In his Nobel acceptance speech, President Carter said, ‘God gives us the capacity for choice. We can choose to alleviate suffering. We can choose to work together for peace,'” Obama said. “He made that choice again and again over the course of his 100 years, and the world is better for it.” But the messages came from across the political spectrum. “I just heard of the news about the passing of President Jimmy Carter,” President-elect Donald Trump wrote on his Truth Social platform on Sunday . “Those of us who have been fortunate to have served as President understand this is a very exclusive club, and only we can relate to the enormous responsibility of leading the Greatest Nation in History,” Trump wrote. “The challenges Jimmy faced as President came at a pivotal time for our country and he did everything in his power to improve the lives of all Americans. For that, we all owe him a debt of gratitude.” President Joe Biden also reacted to Carter’s death, calling him “an extraordinary leader, statesman and humanitarian” in a statement released by the White House . “With his compassion and moral clarity, he worked to eradicate disease, forge peace, advance civil rights and human rights, promote free and fair elections, house the homeless, and always advocate for the least among us,” Biden said. “He saved, lifted, and changed the lives of people all across the globe. “He was a man of great character and courage, hope and optimism,” he said. “We will always cherish seeing him and Rosalynn together. The love shared between Jimmy and Rosalynn Carter is the definition of partnership and their humble leadership is the definition of patriotism.” Follow the latest on President Jimmy Carter’s death Among the scores of others offering condolences was former President George W. Bush, who issued a statement on X through the Bush presidential center . “James Earl Carter, Jr., was a man of deeply held convictions,” the statement said. “He was loyal to his family, his community, and his country. President Carter dignified the office. And his efforts to leave behind a better world didn’t end with the presidency. “His work with Habitat for Humanity and the Carter Center set an example of service that will inspire Americans for generations,” Bush wrote. “We join our fellow citizens in giving thanks for Jimmy Carter and in prayer for his family.” Meanwhile, former President Bill Clinton also honored Carter for being “guided by his faith.” “From his commitment to civil rights as a state senator and governor of Georgia, to his efforts as President to protect our natural resources in the Arctic National Wildlife Refuge, make energy conservation a national priority, return the Panama Canal to Panama,” Clinton said in the statement , “he worked tirelessly for a better, fairer world.” Also commenting was New York’s senior senator. “Today we mourn the loss of one of our most humble and devoted public servants,” US Sen. Chuck Schumer wrote on X . “President Carter personified the true meaning of leadership through service, through compassion and through integrity. “He taught us that the strength of a leader lies not in rhetoric but in action, not in personal gain but in service to others,” Schumer wrote. Carter, 100, was the longest-living former president in US history . He died in his hometown of Plains, Georgia, after spending nearly two years in hospice care — and more than a year after former First Lady Rosalynn Carter, who died at the age of 77. The former president’s death was announced by the Carter Center. The 39th president, a former peanut farmer, remained active in civic duties until he was sidelined by ill health in recent years, including his work for Habitat for Humanity. He was also a former recipient of the Nobel Peace Prize, earning the award in 2002 for his ongoing work as a global humanitarian. In a post on X Sunday House Speaker Mike Johnson also paid his respects. “President Carter’s story was one of humble beginnings, and his life is a testament to the boundless opportunities available in this great nation,” Johnson wrote. “Because of his work in brokering the Camp David Accords and his advocacy with Habitat for Humanity, the world is a more peaceful place, and more Americans have a place to call home. “No one can deny that President Carter led an extraordinary life of service to his country,” he said. Former Vice President Al Gore said Sunday that Carter’s legacy is marked not just by his elected service but also “his leadership over the 42 years after he left office. “It is a testament to his unyielding determination to help build a more just and peaceful world,” Gore said. With P ost wiresTOUCHING tributes for the late Jimmy Carter have started to flood in for the "extraordinary leader" who has died aged 100. Joe Biden and Donald Trump have led the heartfelt messages to the beloved former president whose death was confirmed by his family earlier today. Carter, the oldest president in history , and the only one to become a centenarian, has been survived by five other American commander-in-chiefs who have all left touching homages to the great man. President-elect Donald Trump remembered Carter for his leadership and urged Americans to keep the late president's loved ones in their " hearts and prayers". Trump wrote on Truth Social: "The challenges Jimmy faced as President came at a pivotal time for our country and he did everything in his power to improve the lives of all Americans. "For that, we all owe him a debt of gratitude. Read more on jimmy carter "Melania and I are thinking warmly of the Carter Family and their loved ones during this difficult time." He later posted a second statement which acknowledged the pair's political and philosophical differences but praised Carter's clear love for America. "He truly loved and respected our Country, and all it stands for," Trump added. "He worked hard to make America a better place, and for that I give him my highest respect. Most read in The US Sun "He was a truly good man and, of course, will be greatly missed. He was also very consequential, far more than most Presidents, after he left the Oval Office." The man Trump is set to replace in the White House in just a few weeks time in Joe Biden described Carter as an "extraordinary leader, statesman, and humanitarian". The fellow Democrat and close friend posted the loving tribute alongside his wife Jill. They said: "Over six decades, we had the honor of calling Jimmy Carter a dear friend." "He was a man of great character and courage, hope and optimism. We will always cherish seeing him and Rosalynn together." Joe, 82, has now taken on the title as the oldest living president following the passing of Carter. Barack Obama - the youngest living American leader - commended the late humanitarian with his wife Michelle. They said: "Maranatha Baptist Church will be a little quieter on Sundays, but President Carter will never be far away — buried alongside Rosalynn next to a willow tree down the road, his memory calling all of us to heed our better angels. "Michelle and I send our thoughts and prayers to the Carter family, and everyone who loved and learned from this remarkable man." Former President Bill Clinton and his wife Hillary also praised Carter's commitment to service. They praised him for his "long and good life" and applauded his belief in faith and selflessness. The final remaining president, George W. Bush, joined his wife Laura to call Carter “a man of deeply held convictions” who “dignified the office ". International tributes Tributes to the statesman even came from overseas as the UK's Prime Minister Sir Keir Starmer lauded Carter's service. The British PM said he “redefined the post-presidency with a remarkable commitment to social justice and human rights at home and abroad”. King Charles III also described the former US president as a “committed public servant” who “devoted his life to promoting peace”. Sir Tony Blair soon followed with a powerful statement. It read: "Jimmy Carter's life was a testament to public service; from his time in office, and the Camp David Accords, to his remarkable commitment to the cause of people and peace round the world over the past 40 years. "I always had the greatest respect for him, his spirit and his dedication. "He fundamentally cared and consistently toiled to help those in need." PRESIDENT CARTER Carter , the 39th president of the United States , has died after nearly two years in hospice care. His son Chip Carter confirmed the former president died at his Georgia home on Sunday around 3:45 pm ET. Carter peacefully passed away surrounded by his family who paid an emotional tribute to the former leader. His son Chip said: “My father was a hero, not only to me but to everyone who believes in peace, human rights, and unselfish love. “My brothers, sister, and I shared him with the rest of the world through these common beliefs. "The world is our family because of the way he brought people together, and we thank you for honoring his memory by continuing to live these shared beliefs.” Public events will commemorate Carter in Atlanta and Washington, D.C. and a state funeral will be held, The Carter Center confirmed. The former president decided to live out the remainder of his days at his home in Plains, Georgia . Carter, the beloved Democrat and Nobel Peace Prize winner, had experienced several health issues in recent years including melanoma that spread to his liver and brain. He became the longest-living president and the first to make it 100 years old. Carter's death came over a year after the death of his wife, Rosalynn Carter , who died on November 19, 2023, at age 96. Two days before her death, Rosalynn joined her husband in hospice care at their home in Georgia. The former first lady and fierce advocate for mental health was diagnosed with dementia in early 2023. READ MORE SUN STORIES Before his death, Jimmy Carter was the first to pay tribute to his wife of 77 years, "Rosalynn was my equal partner in everything I ever accomplished. "She gave me wise guidance and encouragement when I needed it. As long as Rosalynn was in the world, I always knew somebody loved and supported me."
Elon Musk is easily the world’s wealthiest man, with a net worth topping $300 billion. But even he stands to make more money from his association with the federal government after placing a winning bet on Donald Trump’s election to the presidency. “It’s going to be a golden era for Musk with Trump in the White House,” Wedbush Securities analyst Dan Ives said. Musk’s aerospace company SpaceX received billions of dollars in federal contracts, and could be in line for more, while his five other businesses could gain from a lighter regulatory touch. Trump named Musk to co-head a new Department of Government Efficiency, or DOGE — a nod to the cryptocurrency Musk adores. However, federal law bars executive branch employees, which can include unpaid consultants, from participating in government matters that will affect their financial interests, unless they divest of their interests or recuse themselves. Trump’s transition team has sought a work-around, saying he would “provide advice and guidance from outside of Government” with the work concluding by July 2026, according to a news release. Richard Painter, a University of Minnesota Law School professor and former chief White House ethics lawyer, said that if Musk is truly working outside the government he doesn’t have to sell his assets, but that limits his influence. “He can make recommendations, but ultimately the decisions are made by government officials,” Painter said. Trump’s campaign and Musk’s companies didn’t respond to requests for comment. Here’s how Musk could benefit from Trump’s presidency. If there’s one Musk business that could profit the most from the incoming Trump administration, it’s SpaceX. The company, which announced this year it would move its headquarters from California to Texas, already received at least $21 billion in federal funds since its 2002 founding, according to government contracting research firm The Pulse. That includes contracts for launching military satellites, servicing the International Space Station and building a lunar lander. However, that figure could be dwarfed by a federal initiative to fund a Mars mission, which is the stated goal of SpaceX. “Elon Musk is wealthy, but he’s not wealthy enough to completely fund humans to Mars. It needs to be a public/private partnership, because of the tens of billions of dollars that this would cost, or even hundreds of billions dollars,” said Laura Forczyk, executive director of space industry consulting firm Astralytical. SpaceX already made big strides testing Musk’s Starship rocket, the most powerful ever built. NASA envisions employing the rocket in its Artemis program to return humans to the moon, but it has been designed to have enough thrust to propel a spacecraft to Mars. What’s more, Trump, during his first presidency, speculated on Twitter about why the United States was focusing on the moon instead of Mars. Still, there are technical challenges, with SpaceX yet to complete the $4 billion Starship lunar lander, which would have to be modified for Mars. And without a pressing geopolitical threat, Congress may be unwilling to spend more on space exploration, as it did during the 1960s with the Apollo program, Forczyk said. Should a Mars project not materialize, SpaceX could still reap rewards in the next four years. For example, the Federal Communications Commission denied SpaceX nearly $900 million in federal subsidies to provide rural broadband access through its Starlink satellite network. Under new FCC leadership, Forczyk sees that being reversed. Trump’s policies could reduce the sales of electric vehicles, but with Musk’s influence, his administration’s policies could boost Tesla — though not with federal funding. For example, Trump, who tempered criticism of electric vehicles after Musk backed him, might end a $7,500 tax credit for electric vehicles. That would hurt Tesla’s unprofitable rivals that rely more on the tax credits to lure customers. “Tesla is the only automaker that has the scale and scope to price vehicles in a $30,000-to-$40,000 range and make significant profits,” Ives said. “It would essentially take competition out of the market.” Trump’s Republican administration also is considering imposing tariffs on Mexico and China, which could make cars more expensive. Ives said he expects Trump to make exceptions for Tesla and Apple so they’re not hit by a tax on imported goods. Tesla receives only a smattering of federal contracts, according to USAspending.gov , a database that tracks U.S. government spending. This year, Tesla received at least $2.8 million from the Pennsylvania Department of Transportation through a federally funded program to deploy EV charging stations. Musk’s startup xAI doesn’t appear to have federal government contracts, but artificial intelligence companies could benefit in other ways under Trump. Republicans and Musk have expressed support for cutting regulation to fuel AI innovation, a crucial part of the future of tech companies. But Musk has also warned that AI could pose a threat to humanity, and it’s unclear how Trump plans to address potential safety risks that come with technology including fraud, bias and disinformation. X, formerly known as Twitter, served as an online megaphone for Musk, who constantly shared his support for Trump during the election season. The social media site, which recently relocated its San Francisco headquarters to Texas, doesn’t appear to have any federal government contracts, but X could benefit from policy changes that affect its rivals such as Meta and TikTok. Musk, who has declared himself a “free speech absolutist,” recently shared an old Trump video with the words “YES!” In the video from 2022, Trump says he would change Section 230, a law that shields platforms from liability for user-generated content. Platforms would qualify for immunity only if the companies “meet high standards of neutrality, transparency, fairness and nondiscrimination,” Trump said. Fed up with Los Angeles traffic, Elon Musk launched The Boring Co. with two tweets in 2016, promising “to build a tunnel boring machine and just start digging.” The Bastrop, Texas, company, formerly headquartered in Hawthorne, has completed a 1.7-mile loop under the Las Vegas Convention Center and is building a larger citywide loop — both without federal funding. Projects in some other cities didn’t get past the proposal stages. However, at Trump’s urging, congressional representatives could earmark local transportation projects to the benefit of Boring Co., though the company would still have to compete to win them, said Greg Griffin, a former urban planning professor at the University of Texas at San Antonio, who studied that city’s proposed Boring Co. project. Controlling robotic limbs. Seeing without eyes. Those are the kinds of miraculous advances Musk’s Neuralink startup has been trying to achieve. The Fremont, California, company he co-founded in 2016 doesn’t receive federal money, but its technology and clinical trails are regulated by the Food and Drug Administration. The more hands-off approach favored by Trump could aid such medical device developers. “We’re concerned that regulation in general in the FDA will be weakened under the second Trump administration, and particularly concerned about medical devices,” said Dr. Robert Steinbrook, health research group director for the consumer rights group Public Citizen. Get local news delivered to your inbox!
SANTA CLARA, Calif. (AP) — San Francisco coach Kyle Shanahan said linebacker De'Vondre Campbell won't be part of the 49ers moving forward after he refused to enter a game after losing his starting job. Shanahan said the team is still working through the options of how to deal with Campbell, who walked to the locker room in the middle of a 12-6 loss to the Los Angeles Rams on Thursday night when he refused to enter the game. “His actions from the game are not something you can do to your team or teammates and still expect to be a part of our team,” Shanahan said Friday. “We're working through the semantics right now, but we'll handle the situation appropriately." Shanahan said Campbell won't be part of the team for the final three weeks. Teams have the ability to suspend players up to four games without pay for conduct detrimental to the team, according to the Collective Bargaining Agreement. The Niners also could just waive Campbell outright, which would allow him potentially to be claimed or signed by another team. Campbell signed a $5 million, one-year contract with San Francisco in March. Campbell had started 12 of the first 13 games of the season and played 90% of defensive snaps for the 49ers but was benched Thursday night after Dre Greenlaw came back for his first game since tearing his left Achilles tendon in last season’s Super Bowl. When the 49ers wanted to put Campbell in the game in the third quarter because Greenlaw was sidelined with soreness in his Achilles tendon, Campbell refused, something Shanahan said has never happened to him in his time as a head coach or an assistant in the NFL. Shanahan said Friday that he has not gotten any explanation from Campbell on why he didn't play. Campbell then walked off the field with a towel draped over his head and went into the locker room before the end of the game with the Rams that almost ended the 49ers' playoff hopes. Shanahan said he didn't send Campbell to the locker room and didn't know why he left the field. “Once I found out he wasn't playing, I moved on to people we could count on,” he said. Campbell's decision left his teammates angered and bewildered. "He’s a professional,” cornerback Charvarius Ward said after the game. “He’s been playing for a long time. If he didn’t want to play, he shouldn’t have dressed out. He could have told them before the game. So I feel like that was selfish. It definitely hurt the team. Dre went down and we needed a linebacker. ... For him to do that, that’s sucker (stuff) in my opinion. He’s probably going to get cut soon.” Ward is one of several 49ers who has played through injury or personal tragedy during a trying season for San Francisco. Ward’s 1-year-old daughter died on Oct. 28 but he has returned and played the last three games for San Francisco. Tight end George Kittle called Campbell's actions “stupid” and “immature.” “It’s one person making a selfish decision,” Kittle said. “I’ve never been around anybody that’s ever done that and I hope I’m never around anybody who does that again.” The 31-year-old Campbell signed in the offseason with San Francisco after being cut by Green Bay in March. He had been an All-Pro in 2021 for the Packers but his play fell off the last two seasons in Green Bay. That led to Campbell complaining on social media that he was misused by Green Bay. He expressed excitement about being with a new team but he never got back to his All-Pro level. Campbell had a few bright moments in San Francisco this season but struggled frequently with tackling and in coverage. AP NFL: https://apnews.com/NFLTributes pour in after death of Ex-President Jimmy Carter: ‘Humble and devoted public servant’
Skidding No. 10 Kansas hopes to get right vs. NC StateGophers’ blowout of Morgan State underscores U’s weak nonconference slate